ID   W6L3R9_9TRYP            Unreviewed;       598 AA.
AC   W6L3R9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=PI3K/PI4K catalytic domain-containing protein {ECO:0000259|Pfam:PF00454};
GN   ORFNames=GSHART1_T00004746001 {ECO:0000313|EMBL:CCW68073.1};
OS   Phytomonas sp. Hart1.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Phytomonas.
OX   NCBI_TaxID=223615 {ECO:0000313|EMBL:CCW68073.1, ECO:0000313|Proteomes:UP000053358};
RN   [1] {ECO:0000313|EMBL:CCW68073.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Hart1 {ECO:0000313|EMBL:CCW68073.1};
RA   Genoscope - CEA;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCW68073.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hart1 {ECO:0000313|EMBL:CCW68073.1};
RX   PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA   Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA   Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA   Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA   Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA   Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA   Wincker P., Dollet M.;
RT   "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT   Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL   PLoS Genet. 10:e1004007-e1004007(2014).
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DR   EMBL; HF955201; CCW68073.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6L3R9; -.
DR   EnsemblProtists; CCW68073; CCW68073; GSHART1_T00004746001.
DR   OrthoDB; 123948at2759; -.
DR   Proteomes; UP000053358; Unassembled WGS sequence.
DR   GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR   InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR   InterPro; IPR015433; PI_Kinase.
DR   PANTHER; PTHR10048:SF120; 3-KINASE CATALYTIC SUBUNIT, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053358}.
FT   DOMAIN          337..385
FT                   /note="PI3K/PI4K catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00454"
SQ   SEQUENCE   598 AA;  67639 MW;  BD252D9DE02CD6BA CRC64;
     MPHRIAPANV QTAVVYLLDM LNRDADVAIL PSHRIFQSVL ELLLPAFVSA NLQLCFIILF
     SLQSAMSSPR RRYDVELLGL WRTRVLDELG SDQLRAMCEA TLNFFTSLDT FCLQSSAVSN
     QMLVRWIRSY CWDGANSTTA FARTRTRVQV GRRASLNEPF SMHTPFPPSF ATSSLSSAVA
     PVFLNLPFPI LNPFKPWIEL HSVLLTSIRV ESLSSSKPIW ITFSNYSDAE RANRKETRKG
     NSARESEKDE MFFSFLYKRE SALRDQLMCI SSRLLQWLLR NQIGSRVKIG NYSVLPLSDS
     SALIESLEGY TLYKLPGIAN GNLALVTYLT QRGEAALLNF LASAKLFLLL NYIFSIGDRH
     QGNVMMSPVG AILHIDFSYI FSEKTLMEKL AGTSIRVDSQ LLSAVAFCRR ATTNTTASCP
     HLADDALSSS SSSLFLGSPC EGFLEVLNDS ADDRHRNTMM VGDPARPTND NSFQSDNEEF
     FTEAAEWFLR VRPHAALFYE LWRYAVRCQS LPFDERNLAT IFNTLFDRSA SRKSSADSFM
     RAMEHSINVC RLKDATYSSV QTFRSYTDQV VRYVSETPLE ARKLLDYVWN HFNLSRVA
//