ID W6M7B6_9GAMM Unreviewed; 482 AA.
AC W6M7B6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Tyrosine phenol-lyase {ECO:0000313|EMBL:CDI02509.1};
DE EC=4.1.99.1 {ECO:0000313|EMBL:CDI02509.1};
GN Name=tnaA {ECO:0000313|EMBL:CDI02509.1};
GN ORFNames=BN873_310028 {ECO:0000313|EMBL:CDI02509.1};
OS Candidatus Competibacter denitrificans Run_A_D11.
OC Bacteria; Pseudomonadota; Gammaproteobacteria;
OC Candidatus Competibacteraceae; Competibacter.
OX NCBI_TaxID=1400863 {ECO:0000313|EMBL:CDI02509.1, ECO:0000313|Proteomes:UP000035760};
RN [1] {ECO:0000313|EMBL:CDI02509.1, ECO:0000313|Proteomes:UP000035760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Run_A_D11 {ECO:0000313|EMBL:CDI02509.1,
RC ECO:0000313|Proteomes:UP000035760};
RA McIlroy S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDI02509.1, ECO:0000313|Proteomes:UP000035760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Run_A_D11 {ECO:0000313|EMBL:CDI02509.1,
RC ECO:0000313|Proteomes:UP000035760};
RA McIlroy S.J., Albertsen M., Andresen E.K., Saunders A.M., Kristiansen R.,
RA Stokholm-Bjerregaard M., Nielsen K.L., Nielsen P.H.;
RT "Candidatus Competibacter-lineage genomes retrieved from metagenomes reveal
RT functional metabolic diversity.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR611166-50};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC {ECO:0000256|ARBA:ARBA00009721}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDI02509.1}.
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DR EMBL; CBTJ020000038; CDI02509.1; -; Genomic_DNA.
DR RefSeq; WP_048672793.1; NZ_CBTJ020000038.1.
DR AlphaFoldDB; W6M7B6; -.
DR STRING; 1400863.BN873_310028; -.
DR OrthoDB; 9764079at2; -.
DR Proteomes; UP000035760; Unassembled WGS sequence.
DR GO; GO:0009034; F:tryptophanase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR011166; Beta-eliminating_lyase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF001386; Trpase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:CDI02509.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR611166-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000035760}.
FT DOMAIN 55..423
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 266
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR611166-50"
SQ SEQUENCE 482 AA; 54210 MW; AF32457CEF2F08BD CRC64;
MSTVKFFSGE DVPLEMHKVR IVQKLNLPPV DYRLKAITEA GNNTFLLQNR DVFMDMLTDS
GVNAMSDQQQ AAMLVADDSY AGSETYNRLE TKLREIFGLH YFLPTHQGRA AENILSQVLV
KAGMIVPMNY HFTTTKAHIT LNGGSVEEII TDAGLEVTSE HPFKGNMDIG KLTALVEQHG
RDKIAFVRME AGTNLIGGQP FSLQNLADIR QVCDRYNLLL VLDASLLADN LYFIKEREER
CKSLSIREIT RQMAALCDII YFSARKLGCA RGGGICLKTE ELYRKMRGLV PLYEGFLTYG
GMSVREMEAL TVGLEETMDE DMINQGPQFI RYMVDELVKR GIPVITPAGG LGCHLNAMEF
LRHVPQSQYP AGALASALYI ASGIRGMERG TLSEQRDPDG NEVFANMELL RLALPRRVFT
LSQVKYAIDR ITWLHENRGL VGGLEFIEEP EILRFFYGRL KPISGWQEKL LARFQQDFGD
SL
//
