ID W6MKM8_9ASCO Unreviewed; 497 AA.
AC W6MKM8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE RecName: Full=Prenylcysteine lyase domain-containing protein {ECO:0000259|Pfam:PF07156};
GN ORFNames=KUCA_T00002530001 {ECO:0000313|EMBL:CDK26558.1};
OS Kuraishia capsulata CBS 1993.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Kuraishia.
OX NCBI_TaxID=1382522 {ECO:0000313|EMBL:CDK26558.1};
RN [1] {ECO:0000313|EMBL:CDK26558.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK26558.1};
RA Genoscope - CEA;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDK26558.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK26558.1};
RA Morales L., Noel B., Porcel B., Marcet-Houben M., Hullo M-F., Sacerdot C.,
RA Tekaia F., Leh-Louis V., Despons L., Khanna V., Aury J-M., Barbe V.,
RA Couloux A., Labadie K., Pelletier E., Souciet J-L., Boekhout T.,
RA Gabaldon T., Wincker P., Dujon B.;
RT "Complete DNA sequence of /Kuraishia capsulata/ illustrates novel genomic
RT features among budding yeasts (/Saccharomycotina/).";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the prenylcysteine oxidase family.
CC {ECO:0000256|ARBA:ARBA00009967}.
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DR EMBL; HG793127; CDK26558.1; -; Genomic_DNA.
DR AlphaFoldDB; W6MKM8; -.
DR STRING; 1382522.W6MKM8; -.
DR HOGENOM; CLU_021176_0_0_1; -.
DR OrthoDB; 1334100at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001735; F:prenylcysteine oxidase activity; IEA:InterPro.
DR GO; GO:0030328; P:prenylcysteine catabolic process; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010795; Prenylcys_lyase.
DR InterPro; IPR017046; Prenylcysteine_Oxase.
DR PANTHER; PTHR15944; FARNESYLCYSTEINE LYASE; 1.
DR PANTHER; PTHR15944:SF0; PRENYLCYS_LYASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR Pfam; PF07156; Prenylcys_lyase; 1.
DR PIRSF; PIRSF036292; Prenylcysteine_oxidase; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 152..487
FT /note="Prenylcysteine lyase"
FT /evidence="ECO:0000259|Pfam:PF07156"
SQ SEQUENCE 497 AA; 54807 MW; F2AA5FB43114C7FC CRC64;
MSSLGQKANR YILIFGVMTL VPLVFLAYSL SLVWGNSCGA SPPSSDSIGA ERIAIIGAGA
GGSSCAYYLQ KFTSFGYNIT VFERSNYVGG RSTTVRAKNS STLVELGASI FIGDNEIMMN
AVETFGLDHH DFSTSDEFLI WNGEEALYTY QDSSIPYYSQ TKLLLRYGLS YFSAKTLVSG
IVDKFLTYYY SDYFPFPSLT KLSLTTGFSE LTGETSETFF TSNNIGSLYL HEIIEAVTRV
NYAQNVNQIH ALGASVCMAA GSAYSVTGGN WQVFDSFIKV SEANLLLQHG VASIKKNAQS
NFEVTAVDSS GYEFTEEYDQ VVIAAPYYQT NINLPTGYSS EVENRQYVEL HVTLLTTFGT
LSKSYFNADY VPTTVITSSE GAQKNTPFFS ISKVGNISET TESIYKIFSP AELSDKFITT
LFEKGSTISW VHRKTWKPYP YLKPTTQFTD FQLDQDGLWY LNGMEEFIST METSALAGAN
VAALISKGKN TTFLTVP
//
