ID W6MPK4_9ASCO Unreviewed; 633 AA.
AC W6MPK4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=KUCA_T00003034001 {ECO:0000313|EMBL:CDK27057.1};
OS Kuraishia capsulata CBS 1993.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Kuraishia.
OX NCBI_TaxID=1382522 {ECO:0000313|EMBL:CDK27057.1};
RN [1] {ECO:0000313|EMBL:CDK27057.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK27057.1};
RA Genoscope - CEA;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDK27057.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK27057.1};
RA Morales L., Noel B., Porcel B., Marcet-Houben M., Hullo M-F., Sacerdot C.,
RA Tekaia F., Leh-Louis V., Despons L., Khanna V., Aury J-M., Barbe V.,
RA Couloux A., Labadie K., Pelletier E., Souciet J-L., Boekhout T.,
RA Gabaldon T., Wincker P., Dujon B.;
RT "Complete DNA sequence of /Kuraishia capsulata/ illustrates novel genomic
RT features among budding yeasts (/Saccharomycotina/).";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HG793127; CDK27057.1; -; Genomic_DNA.
DR AlphaFoldDB; W6MPK4; -.
DR STRING; 1382522.W6MPK4; -.
DR HOGENOM; CLU_009281_2_2_1; -.
DR OrthoDB; 2734344at2759; -.
DR UniPathway; UPA00618; UER00672.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|RuleBase:RU003733};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 76..327
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 336..553
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 633 AA; 69758 MW; B889D3FE25F35324 CRC64;
MSPAHFTAFE NLVVSVDVGT TSTRAIFFRK DGSHVASHQI EYSTSAREAS KRNSPEIFTP
EGVAISLSDS VEIESRINEP TLVFPNPGWV ECDPIQVLGN VIQCLAACLV QLATTEHDVQ
FKISAIGIAN MRETTIVWSK RSGRPLHNGI VWNDTRTSKL VADIYQNEST ERIDRVRELG
GCPISTYFSA TKWRWLYENV PHIRKAYDQG DGDLMFGTVD TWLIYCLTEE SSFVTDVTNA
SRTSLMNIET HRYDDELLSF WNIDRSKLQL PDIRPSSYVY GHYHTPDLRA LGTTQFHLSI
DARAVLQMLH GVPIAGCLGD QSASLVGQLA VKQGDAKCTY GTGAFLLYNT GPRILASQHG
ALTTVGYWFP QLKSENEDGD EDCNKPQYAL EGSIAVAGSV VQWLRDNLRL ISNSKDVGPL
ASQVSNSGGV VFVPAFSGLY APYWDSGSRG TILGLTQYTS AAHIARAALE AVCYQVRAIL
KAMISDTGSS PEFLDDRNLS AADNPLSSLR VDGGMSKSNE MMQIQADILG PCVTVIRSAN
HECTALGAAI AAGLCSEGED SEPFMWNSLK EAVRMVSGGG DLSAEEPSDN TFHAELSDAK
RRRMWKLWER GVERSRGWEI NDDDYDRDEE MED
//
