ID   W6NBN5_HAECO            Unreviewed;       150 AA.
AC   W6NBN5;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=RNA-directed DNA polymerase (Reverse transcriptase) domain containing protein {ECO:0000313|EMBL:CDL94708.1};
GN   ORFNames=HCOI_01142600 {ECO:0000313|EMBL:CDL94708.1};
OS   Haemonchus contortus (Barber pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6289 {ECO:0000313|EMBL:CDL94708.1};
RN   [1] {ECO:0000313|EMBL:CDL94708.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISE/inbred ISE {ECO:0000313|EMBL:CDL94708.1};
RA   Aslett M.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CDL94708.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISE/inbred ISE {ECO:0000313|EMBL:CDL94708.1};
RA   Laing R., Kikuchi T., Martinelli A., Tsai I.J., Beech R.N., Redman E.,
RA   Holroyd N., Bartley D.J., Beasley H., Britton C., Curran D., Devaney E.,
RA   Gilabert A., Jackson F., Hunt M., Johnston S., Kryukov I., Li K.,
RA   Morrison A.A., Reid A.J., Sargison N., Saunders G., Wasmuth J.D.,
RA   Wolstenholme A., Berriman M., Gilleard J.S., Cotton J.A.;
RT   "The genome and transcriptome of Haemonchus contortus: a key model parasite
RT   for drug and vaccine discovery.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL94708.1}.
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DR   EMBL; CAVP010058462; CDL94708.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6NBN5; -.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR47027; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47027:SF8; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Nucleotidyltransferase {ECO:0000313|EMBL:CDL94708.1};
KW   RNA-directed DNA polymerase {ECO:0000313|EMBL:CDL94708.1};
KW   Transferase {ECO:0000313|EMBL:CDL94708.1}.
FT   DOMAIN          1..126
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
SQ   SEQUENCE   150 AA;  17181 MW;  8FF9D58C403DD4E6 CRC64;
     MLRELYNNFT TRISPFYEEV IINVKRGVRQ GDTISPELFS AALENVMRHM EWESMGVKVD
     GRYLHHLRFA DDIVLITPNI EQAEQMLAEF DNACGKIGLR LNLTKTMFMR NGLVPDAPFM
     LNGTNISECS SYVYLGRKVN MMNDLAPELS
//