ID W6PYS8_PENRF Unreviewed; 437 AA.
AC W6PYS8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 03-MAY-2023, entry version 39.
DE SubName: Full=Arf GTPase activating protein {ECO:0000313|EMBL:CDM29423.1};
GN ORFNames=PROQFM164_S01g003235 {ECO:0000313|EMBL:CDM29423.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM29423.1};
RN [1] {ECO:0000313|EMBL:CDM29423.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM29423.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
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DR EMBL; HG792015; CDM29423.1; -; Genomic_DNA.
DR AlphaFoldDB; W6PYS8; -.
DR STRING; 1365484.W6PYS8; -.
DR OMA; MSKLWEV; -.
DR OrthoDB; 389572at2759; -.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08830; ArfGap_ArfGap1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 10..135
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 133..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..427
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 46590 MW; 47A6472AFD57B6F6 CRC64;
MSRMWEVDPE TRTKLLQISK TNGNDKCCDC GAPSPQWASP KFGTFICLNC AGTHRGLGVH
ISFVRSITMD AFKHSEIQRM ELGGNEPWKS FYDEHPVTVS EGRTFEDSTI KERYDSDEGE
EWKERLSCKA DGREYVQGQE KKNNAPSRSN TTSKLTGTTV AGAGAVAGGR AGSPAASSIR
SGDSLRGVPG KKEQNEAYFA KLGNENATRV DSLPPSQGGK FTGFGGGMPA PAASDRRTSP
FGGFGGWGVG GGGGGGGGQP FEDLQKDPLG TITKGLGWFT STVGKSAKQV NDAYLQPTAK
QLAESEFAAQ ARLHAATLGQ GLQTGVRGAA DQFNKFVEGE DGRGDGRRNR VEPERRDFWD
DFASMGDQET PSHRRSASQR SQRSQRSDVV GTAAMRKSPT ASSLGHSTPG LSGEAGEGKN
TTASATGKGK DEWDDNW
//
