ID W6Q0G6_PENRF Unreviewed; 705 AA.
AC W6Q0G6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Anaphase-promoting complex subunit 8 {ECO:0000313|EMBL:CDM29745.1};
GN Name=cut23 {ECO:0000313|EMBL:CDM29745.1};
GN ORFNames=PROQFM164_S01g003558 {ECO:0000313|EMBL:CDM29745.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM29745.1};
RN [1] {ECO:0000313|EMBL:CDM29745.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM29745.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HG792015; CDM29745.1; -; Genomic_DNA.
DR AlphaFoldDB; W6Q0G6; -.
DR STRING; 1365484.W6Q0G6; -.
DR OMA; PQYLSAW; -.
DR OrthoDB; 3131281at2759; -.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF13181; TPR_8; 3.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 12..328
FT /note="Cdc23"
FT /evidence="ECO:0000259|Pfam:PF04049"
FT REPEAT 389..422
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 423..456
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 457..490
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 113..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 79895 MW; 61396A3EE90E1D37 CRC64;
MEEPTDDGIR ELMYQLENAA IKCSERCLYQ SSKWAAEMLD SLRPLDHEDT DLESPMDISD
PPPATNPYLK VRDPVEAALE TQESYKYLLA KSYFDTREYD RCAAVFLPPT TPPVPLSITS
PNSKPRPSRT SHKGKDKASP FQSSKTQKTQ IQQNPYPKLS QKSLFLALYA KYLAGEKRKE
EETEMVLGPA DGEMAVNREL SGLARGLDGW LSERTAQGLD DQGQGWLEYL YAVVLLKGRN
EELAKKWLIR CVHQNPYHWG AWQELNDLLG STEDLKQILE LLPQNVMSLI FYVYCSQELY
QATEDTYRSL SELQSMFPES AFLKTQHALL LYHSKDFEEA SHIFEGILAT SPHRLDSLDH
YSNILYVMDQ RPQLAFVAQV ATATDKFRPE TCCVVGNYYS LKSEHEKAVM YFRRALTLDR
NFLSAWTLMG HEYIEMKNTH TAIESYRRAV DVNRKDYRAW YGLGQAYEVL DMSFYALFYY
QRAAALRPYD PKMWQAVGSC YAKMGRVEQS IQALKRALVA GSLQPDDGGQ SATGASAGSG
SRKILDPETL HQIATLYERL GDEEEAAAYM ELTLQQESGA PVNENADDDD TSVSEHGIQS
DAEIEHSGDE DTDQSQRHRR NRKPRAKAES LAMQNDDSIV SDTWNGTGVT TTTSKARLWL
AQYASRNGDL DRADQLASEL CQDGIEVEEA KALMRDVRAR REDAT
//
