ID W6QHB5_PENRF Unreviewed; 318 AA.
AC W6QHB5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Mitochondrial dicarboxylate transporter {ECO:0000313|EMBL:CDM35361.1};
GN Name=DIC1 {ECO:0000313|EMBL:CDM35361.1};
GN ORFNames=PROQFM164_S04g000242 {ECO:0000313|EMBL:CDM35361.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM35361.1};
RN [1] {ECO:0000313|EMBL:CDM35361.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM35361.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; HG792018; CDM35361.1; -; Genomic_DNA.
DR AlphaFoldDB; W6QHB5; -.
DR STRING; 1365484.W6QHB5; -.
DR OMA; FGAYEVG; -.
DR OrthoDB; 2086232at2759; -.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-KW.
DR GO; GO:0005310; F:dicarboxylic acid transmembrane transporter activity; IEA:UniProt.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45618:SF13; MITOCHONDRIAL DICARBOXYLATE CARRIER; 1.
DR PANTHER; PTHR45618; MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00784; MTUNCOUPLING.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT REPEAT 27..112
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 124..215
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 224..311
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 318 AA; 34511 MW; 926D75CF04FE1A81 CRC64;
MADSGKMLEV PPHSRVVPVQ PAQSKPKQVH YPFWFGGSAS CFAAAVTHPL DLVKVRLQTR
APDGPKNMVG TFVHILKHNG VTGLYSGLSA AMLRQITYST TRFGIYEELK SRISPPTSDP
AAAPGLLTLI GIASASGFIG GIAGNPADVM NVRMQHDASL PPAQRRNYRN AIHGLIQMTR
TEGFGSLFRG VWPNSTRAIL MTTSQLATYD TFKGLCMEKA GMADNLGTHF TASFMAGFVA
TTACSPVDVI KTRIMTASHA DSGGHTIVGL LRDICRKEGL GWTFRGWVPS FIRLGPHTIA
TFLFLEEHKK LYRKLKGI
//
