ID   W6QRV9_PENRF            Unreviewed;       288 AA.
AC   W6QRV9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=E3 binding {ECO:0000313|EMBL:CDM32257.1};
GN   ORFNames=PROQFM164_S02g002408 {ECO:0000313|EMBL:CDM32257.1};
OS   Penicillium roqueforti (strain FM164).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM32257.1};
RN   [1] {ECO:0000313|EMBL:CDM32257.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FM164 {ECO:0000313|EMBL:CDM32257.1};
RX   PubMed=24407037; DOI=10.1038/ncomms3876;
RA   Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA   Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA   Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT   "Multiple recent horizontal transfers of a large genomic region in cheese
RT   making fungi.";
RL   Nat. Commun. 5:2876-2876(2014).
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00007317}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HG792016; CDM32257.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6QRV9; -.
DR   STRING; 1365484.W6QRV9; -.
DR   OMA; DGIMMKI; -.
DR   OrthoDB; 52212at2759; -.
DR   GO; GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IEA:InterPro.
DR   Gene3D; 4.10.320.10; E3-binding domain; 1.
DR   InterPro; IPR045257; E2/Pdx1.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   PANTHER; PTHR23151; DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR23151:SF82; PYRUVATE DEHYDROGENASE COMPLEX PROTEIN X COMPONENT, MITOCHONDRIAL; 1.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 1.
DR   PROSITE; PS51826; PSBD; 1.
PE   3: Inferred from homology;
FT   DOMAIN          41..81
FT                   /note="Peripheral subunit-binding (PSBD)"
FT                   /evidence="ECO:0000259|PROSITE:PS51826"
SQ   SEQUENCE   288 AA;  30326 MW;  A6D115816B745EDF CRC64;
     MAARITVGQV PAMFARRQPK VFGVGRRLQS TSITTQNIAY PLYPSVAQLL REKGIPESDV
     SKIPASGPKG RLLKGDVLAY IGKIPANYPS NQAATLAKLT HLDLSNIKIA APAAPAAPAV
     PEKKVVAEPP RLTSVAISIS LAAVLSAQKK LQDNLGVTVP LSRFLAVATD LANDDLPRPA
     NSKPSADELF DEILGAEPIN TSRGDYVPDL NAFDAPKSVR SKPVTEDLIG FLSAKPSKKS
     APAASVESAG VASNVFSLTV PAGEEVRAKA FLERIKTLLS VEPARLVL
//