ID W6RVP5_9CLOT Unreviewed; 455 AA.
AC W6RVP5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative permease MJ0326 {ECO:0000313|EMBL:CDM68388.1};
GN ORFNames=CM240_1224 {ECO:0000313|EMBL:CDM68388.1};
OS Clostridium bornimense.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1216932 {ECO:0000313|EMBL:CDM68388.1, ECO:0000313|Proteomes:UP000019426};
RN [1] {ECO:0000313|EMBL:CDM68388.1, ECO:0000313|Proteomes:UP000019426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M2/40 {ECO:0000313|Proteomes:UP000019426};
RA Wibberg D., Puehler A., Schlueter A.;
RT "Complete genome sequence of Clostridum sp. M2/40.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC ECO:0000256|PIRNR:PIRNR005353}.
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DR EMBL; HG917868; CDM68388.1; -; Genomic_DNA.
DR RefSeq; WP_044037415.1; NZ_HG917868.1.
DR AlphaFoldDB; W6RVP5; -.
DR STRING; 1216932.CM240_1224; -.
DR KEGG; clt:CM240_1224; -.
DR PATRIC; fig|1216932.3.peg.1216; -.
DR eggNOG; COG2252; Bacteria.
DR HOGENOM; CLU_024508_0_1_9; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000019426; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR026033; Azg-like_bact_archaea.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PIRSF; PIRSF005353; PbuG; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW Reference proteome {ECO:0000313|Proteomes:UP000019426};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 455 AA; 47924 MW; 486CC094D5A2E839 CRC64;
MENLSPKERI LPILSNKKVD YKKEVVAGIT TFLTMAYIIA VNPQILGATG MDQGALVTAT
CLTAAIGCIL MGIFANLPFA LASGMGLNAY FAYSVVIGKG ISWEVALTAV FVEGIIFILL
SLFKVREAVV NAIPKNLKLA VTGGIGLFIA FVGVQGSGLV VNDDSTLVAM GSFTPAVVIS
LVGLIIIAVL DKKKVKGAIL YGIAVSSILA WGIAIIDADY AAKLSIYLPN GLFKFESISP
IAGKLDFGYA FHKDTIATFI TIVCTFLFVD FFDTVGTLVG VASKAKMLDK DGKLPGVGRA
LLVDAVSTTA GAAMGVSTVT TYVESSTGVA AGGRTGYTAI TTGVLFFLAM FFSPIFVAIP
SCATAPALMY VGYLMLGVVK DIDFDNITEG VPAFLTIAAM PLTYSIGDGL TLGVLSYVII
NILYNIFAKK DEKKANVSWV MIILAVLFIF KIAFL
//
