ID W6SFY2_9CLOT Unreviewed; 290 AA.
AC W6SFY2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Farnesyl diphosphate synthase {ECO:0000313|EMBL:CDM68610.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:CDM68610.1};
GN Name=ispA {ECO:0000313|EMBL:CDM68610.1};
GN ORFNames=CM240_1451 {ECO:0000313|EMBL:CDM68610.1};
OS Clostridium bornimense.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1216932 {ECO:0000313|EMBL:CDM68610.1, ECO:0000313|Proteomes:UP000019426};
RN [1] {ECO:0000313|EMBL:CDM68610.1, ECO:0000313|Proteomes:UP000019426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M2/40 {ECO:0000313|Proteomes:UP000019426};
RA Wibberg D., Puehler A., Schlueter A.;
RT "Complete genome sequence of Clostridum sp. M2/40.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; HG917868; CDM68610.1; -; Genomic_DNA.
DR RefSeq; WP_044037802.1; NZ_HG917868.1.
DR AlphaFoldDB; W6SFY2; -.
DR STRING; 1216932.CM240_1451; -.
DR KEGG; clt:CM240_1451; -.
DR PATRIC; fig|1216932.3.peg.1444; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_1_9; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000019426; Chromosome 1.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000019426};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:CDM68610.1}.
SQ SEQUENCE 290 AA; 32448 MW; D184C5402FF5CBDE CRC64;
MSIGEYKKCI DRELKLYFED KIKYSEEEKI IYEAMAYSTN IGGKRIRPIL FMATHNIFSN
SEVPMGIPCA IEMIHTYSLI HDDLPDMDND DLRRGKPTNH KVFGNAMAIL AGDGLLNEAF
NIAFQYVVDH PHHAKALKYL CNSSGVDGMI SGQVIDILNE NKTVSLKELE KMHRLKTGAL
IKASIVSGAI IGGATEEEIV LLEQYGDALG LAFQVIDDIL DVTGNEDKIG KKVGSDATNN
KSTFVSVIGL EESKVYAEKL TLKCYDILEN IDKNTDELYE ITRYLLNREE
//
