ID W6TYK2_9SPIR Unreviewed; 666 AA.
AC W6TYK2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=BDCR2A_00174 {ECO:0000313|EMBL:ETZ18201.1};
OS Borrelia duttonii CR2A.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC Borrelia.
OX NCBI_TaxID=1432657 {ECO:0000313|EMBL:ETZ18201.1, ECO:0000313|Proteomes:UP000019148};
RN [1] {ECO:0000313|EMBL:ETZ18201.1, ECO:0000313|Proteomes:UP000019148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR2A {ECO:0000313|EMBL:ETZ18201.1,
RC ECO:0000313|Proteomes:UP000019148};
RA Schwan T.G., Raffel S.J., Porcella S.F.;
RT "Comparative genomics of relapsing fever spirochetes.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|RuleBase:RU362066}.
CC Periplasmic flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETZ18201.1}.
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DR EMBL; AZIT01000001; ETZ18201.1; -; Genomic_DNA.
DR RefSeq; WP_038366019.1; NZ_AZIT01000001.1.
DR AlphaFoldDB; W6TYK2; -.
DR PATRIC; fig|1432657.3.peg.169; -.
DR Proteomes; UP000019148; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ETZ18201.1};
KW Cilium {ECO:0000313|EMBL:ETZ18201.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:ETZ18201.1};
KW Periplasm {ECO:0000256|RuleBase:RU362066};
KW Reference proteome {ECO:0000313|Proteomes:UP000019148}.
FT DOMAIN 14..109
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 392..650
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 666 AA; 75669 MW; 0DFFCF2A80EBF6F3 CRC64;
MSSGFFVPGV DNKYNTKEIR ESMLKPDKSK IDSSVQKLES LQQEKRAWQT INKKVSVLNS
LAKQITSLDG PFNYMSGNSS NNDVLSVSAR YGAKNENYKI GVNQVASSDV FLSANFKQKE
INIPAGEYTF LVGKKEIKIR NNGDLESLVR DVNNRGKGFL SAKIVKSDSS GNSRLILQSL
KEGENNRLIM KDEALNLAKK IGILSERTTN FSPNIREIVN SQQNSSNKIF LDKDDIVLEP
LSEIAISIPD NIEIGKGSKI KFEIKYYDMD DKSILNEIVF NPGEATFEGA KVEGEDSIIN
LESDYKPFLK EKKYIQMNMI KIHSGTGSLE LPPINVASDF EKVEVEVGSL LGLKEINIEN
KLNNKAFVIR NIEIFDPKNR DGHLPINAKS FAENAKMKFD GVDVERDSNT INDLIPNVTL
NLKQSSDDTV DVRVEPDYEG IRKLLLDFLI AYNEVLAGIN IVSLNEDNVD TQKSDLLEEW
SYLNEEEKEE AYKNLGILRS EFTLKNLKSR LESIMFNVYR TNDPNFSLIN QMGVFTSSMS
SSGGFSRYLK LDEKKFNEVL QSNISSVKEF FAFDFNDDRI YDDGLAKVLG DYLSLLIGAG
GFIYNKIKSY DFRIPNQKNV VEDYKRKYED RERKVEGELN TLDFTVKRMK EQEEILKSLN
LYRQNK
//
