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Database: UniProt
Entry: W6U4N9_ECHGR
LinkDB: W6U4N9_ECHGR
Original site: W6U4N9_ECHGR 
ID   W6U4N9_ECHGR            Unreviewed;      3636 AA.
AC   W6U4N9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   10-MAY-2017, entry version 15.
DE   SubName: Full=Ryanodine receptor 44F {ECO:0000313|EMBL:EUB56108.1};
GN   ORFNames=EGR_09047 {ECO:0000313|EMBL:EUB56108.1};
OS   Echinococcus granulosus (Hydatid tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB56108.1, ECO:0000313|Proteomes:UP000019149};
RN   [1] {ECO:0000313|EMBL:EUB56108.1, ECO:0000313|Proteomes:UP000019149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24013640; DOI=10.1038/ng.2757;
RA   Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA   Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA   Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA   Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y.,
RA   Wang S.;
RT   "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL   Nat. Genet. 45:1168-1175(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EUB56108.1}.
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DR   EMBL; APAU02000129; EUB56108.1; -; Genomic_DNA.
DR   Proteomes; UP000019149; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 2.
DR   SMART; SM00449; SPRY; 2.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 4.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000019149};
KW   Receptor {ECO:0000313|EMBL:EUB56108.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019149}.
FT   DOMAIN       49    103       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      230    297       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      303    362       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      380    438       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN     1102   1339       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   3636 AA;  397138 MW;  39CC7905E7F3D3B9 CRC64;
     MAYPNAYAWV PPANMPPCIF ILEQALSARA LQEMLSSRNE LSDSHTSGHR TLLYGHAIRL
     KHRNSSMYLA CLGTSSTEDK LAFDVGLERK ANTEACWWTI HPASKQRSVG EKVRIGDDLI
     LVSVSSERRC MQVAFGGAIF FPSALSITLC ILACMRARAN GEAANRWPCA DARERVNWCI
     QAGVFWGPSL RDCACHVYGD SFSSSGVIAS FQQTLWTVIP VSSGAVRQKS LHMAFGGDVV
     RLFHGDECLT IQAAGDTEEG QIISNEAASS SDYHQSVMYQ LGSVSGHASS LWQIEHTKIK
     WCAGFFSWED AVRLRHVTTG RYLGITRSGA GGNPSAPGQI DVVLLSPSES DDAATVFYIK
     QTKDDKKKVE IDREHEGMGE PDVCLGETLI YLQHAALGWW LSYESYETKK RGVGKVEEKK
     AVLLAEGHMD DVFSLVRAQE EESLSAAAIR RSTAVFSAFN RSLDALASSD GLGGGGGGAA
     GAASSPATGP GDVPLNLDEV NQCLEDLIEF FAQPETHEEH EARQSKLAAL ANRQDLFQEE
     GMISLVLETI DKFTGTFRSR RDFALAVGEE RGSRFSDLGN YLYLLLAALI RGNRENCAQF
     AAPARLDWLF NRLELQQSFA EGVLDALHCV LTDSDEALNV ITAQHIHTLI GLLDKQGRDP
     RVLEVLYSIC IGRQGGAVRL NQDLIYESLL PERDLLLQTK LVAQSGSMRP NIFVGIKPGG
     SMYTKWYFEV FIDALENVTH QPPGIRIGWG NTDGYTPHPV GGPGWGGISL GDDFYSFAFD
     GQNLWTGGKA KQALFPPGTG GKGLNRRTGA SPPAVSTTSS NGSANLKRGD VIGCLLDLTG
     PVIQFNLNGN LVKGYFQDFN TTGLFFPCVS MTARASARFV LGGTHGKLKH GPPAGYAPII
     DALQPSQRLR LEPVFSFGRL DKSIFSGPLA SPLPSQDVFV PVPISTDKIH LPNVVERIRD
     KLAENLHELW SMRKIEQGWA FGERRDEGRR RHPCLCAFDK LQQQERQYNV TMALENLKTI
     FALRYNIGYE SLPEGTRMRT IKLGASYTQS NGYKPQPLDL SAIRLSSRLE TLVDELAENT
     HNIWAKDRIH QGWTYGSTED NTQKRSPHLV PYSEVNANIK KMNRESATDA VKTLLAYGYV
     IEPVSGESEQ TRENPLDVLE EATMNYRAAS SKAVTRGKWY YEVELLTYGM VRVGWATKNA
     PAATTTGMSG SSYSFAPEQL KLIGGFLLIN RSALNTPLDK VEDWFISRLL MLLWSLLQAR
     KYHRDGRPYG KRCEPGDVIG CMLNLNERSI TFSLNGEIMM DPMGQEIAFK DIKVNHGFVP
     AFTLGSGQQV RINFGNVVQT LKYFTICGLQ EGYSPFAVNM SHPVPMWYSK VDASLFRDLK
     PNHSRLETKV SGAYPPVINI LAKSPSPTGL HQMEYLRLSL GIQCKSHFTT RSLADRRANL
     DHLRKQLEPE DYHHHGIGMG GPANIDLMTQ EIGAAGLEVR DRRGKRARLA NVFRKTRPRD
     VSPDVTSGYS AGAGGVSLVS GSASTSGIVG GKKGDPATAS QTSTGAHEGS PGPAGEEFEL
     LLPEQSALDN AIADFMDEFA YTVLIPPGQN PCLVNVGWVG SCFKISKPAS ISGGNPFPVD
     PDFNVTQLAT TPAPIAKSTV EGDATSVASE SSASEKTSTL GSTTETDKFL NFAEVRQVAV
     CLLHDDLTLK SAVAERSSFL VNVGDLIQKI STPEDIGKRV SQGLAVTCWV DTASGTLGFR
     LNDRDTLIRF QVEPSTHLFA AVFVRPTARD CVQFELGRRS RYHLPLTAGM LRPPRRANMP
     MPHRLNVQAI ERVHWAPVPV EQSKIQSMKM SDQRGWSMLL ENSAPRLVIQ LPEANRCFSI
     LELEEMPDLL KFHAKTLALY CALCCHGNHN VAQKLTSHVD QYQFLYVIQS KYVHGSLRSE
     FVKLLLSMHL ESPMKLKQVT GREFIVPLEK DDLEVTKSPA HVLKIVYDWD PDHIPAVKEH
     RSIRPKLITD PYLLIPGADG TGVGNFTIPT GGGEAQPETV LNAAMAAAGP GGLIKLSDCP
     PFPLDLLKRQ TLDALIDMAN TGGHVRDPFG GNFEHALLPL LLILNHLLVM GSLDAADLAT
     VLGLLSPKLF PNTPSWRVTP ITGSLLELPL PESVKMEVCH LFHHLCDLQL RHRIESIVNF
     ANTAVSEIQN DQLQRYLAIK VANLPSAVAA PRTREFRCPP NVQIRNLLHM PGPGGPSGLL
     EEASCASASS DNEAITVLDL SDSSDDLTLD GYSRNPCAEE IKELMRLFHH RLMNHLGVVK
     PGIEDTWDYE GAIKFLQEAA AAGLQQLTPT SNTVNVTTPN ATATSLTTSA STDSARHTTT
     STTNTSLASS SSEQLQSELT ELLNIPTLLL PEGVGDPESG ASGPPSAVKA IWKLVSGSSD
     TSTANVDGGS GASRQLALGG PEESKQHGRK LHQLILETVS DWASSSIIED VELIRQMFYL
     LYRQYGALDE ASGSSKNTIT KENLRLGLTR TYAIGNRSKE DVSRLLRSLG RIRCLLGVQV
     GANEEILLKN CLWDIMNNNV FFQHPDLIRV LAVHETVMQL MVHTLSKASL DSPSVAATAA
     AAAASTASEL QHQGSLSPQL NAADAISLRR RQGSGGGAEL PVLVEEGEEA TLSGSNLGRN
     VPVGPTEMVV QCCRFLCYFC RTSWQNQKAM FDHLSYMLEN SSMLLARPSL RGICPLDVAY
     SSLMDNNELA LALREKQLEK VAVYLSRCGV QSNAELLTKG YPDIGWDPVE GERFLDFLRF
     TVWVNGESVE ENANLVVRLL IRRPECLGPA LRGGTKSVSS RRQRLNSQSI GQSVVVGSGG
     GGSEGMDQLA PPGSPDAAGG GGAGGGPGGG VNSAGSTTGG VDDAHSTTAS NANAASSSTG
     GGLLKGIKEG IVMSAQIKLV KMAMDAEAQG LNPEDEDMGW RTVLMDYEDC NLFAPLPYNF
     SSLPPEEDED YVDLGAAILT FYAVLVDLLG RCAPELDASK SESVRGRAIL QSLVSMQDLE
     GVLSLRFILP PPKLEMQMNA EGLEQWVDRS PMPPGLLPEH KAAVVLFMER VYGLTDSDTF
     VRLLENAFLP DMRAVTLLDS AQRGVTASDM TLALNRYICG SVLPLLTRYA HFLAVNEVTA
     GLLESTLHTA YRLATCRSIT NNQRDVVSDF LVALVEHIQP FSMTSLIRKI AKNMRIVGRE
     SVVSLRVLTT FYQRFGAYYS SEGWTAEYSS GGGDTKVGVG VGSGGGSSGG ASKPSRTQRV
     SVAGSGAMRD LSDTSFVRST AVGTTATATE EEKNLTAELF SLIFNNLSCR RYDAELYVYA
     LPCLTAIGCA LPPDYCSSHW DAQSRIGEDD TMGLDVSVHP GGPDSAADLR GSNQQHESFR
     PTPLVTSSIK LPAALSILVD QFAKHCHDTW AQELVDQGYI YGLTLDEARR THPNIRSYHS
     LSQRDQMRYI QPVTETLRAM LALGWTIDPS GVCHEDDGTG LGHRRRQFIH SQTESPQGYI
     PAPKDLHGVN VTRELIDLAE RLADNAHQIW AKQKMEELEE IGGGVHQLLV PYDILTDRER
     KRYRRLTHEL IRYLQYWGYR LSYKPTNQQV DTTKTGPAAT TNATPNAIKQ FAGERGEGEC
     GRVVVAGWGI VGQWGIVFKT RRDTDVWQAV TLRRVF
//
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