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Database: UniProt
Entry: W6U5Q3_ECHGR
LinkDB: W6U5Q3_ECHGR
Original site: W6U5Q3_ECHGR 
ID   W6U5Q3_ECHGR            Unreviewed;      1300 AA.
AC   W6U5Q3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   05-JUL-2017, entry version 23.
DE   SubName: Full=Transient-receptor-potential-like protein {ECO:0000313|EMBL:EUB56488.1};
GN   ORFNames=EGR_08665 {ECO:0000313|EMBL:EUB56488.1};
OS   Echinococcus granulosus (Hydatid tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB56488.1, ECO:0000313|Proteomes:UP000019149};
RN   [1] {ECO:0000313|EMBL:EUB56488.1, ECO:0000313|Proteomes:UP000019149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24013640; DOI=10.1038/ng.2757;
RA   Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA   Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA   Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA   Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y.,
RA   Wang S.;
RT   "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL   Nat. Genet. 45:1168-1175(2013).
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00788929}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EUB56488.1}.
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DR   EMBL; APAU02000114; EUB56488.1; -; Genomic_DNA.
DR   Proteomes; UP000019149; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; SSF48403; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00844120};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019149};
KW   Ion channel {ECO:0000256|SAAS:SAAS00816195};
KW   Ion transport {ECO:0000256|SAAS:SAAS00816776};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:EUB56488.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00816535}.
FT   TRANSMEM    592    615       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    627    649       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    706    728       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    795    817       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      173    252       ANK_REP_REGION. {ECO:0000259|Pfam:
FT                                PF12796}.
FT   DOMAIN      312    374       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      660    860       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1300 AA;  145716 MW;  2FA5C715547E6EBB CRC64;
     MTTMNLSGTV LSNSHSNESS STSNMGSRNT MMHSPGKRGN EEVDRRHTPS SSISLGTSKA
     SRSNSYLYQQ TETVPPRSSG KLYLQPKEMP DFGEGTDQKV LPLPPVRSTP TDWFSHSPDR
     SCSSATNIDN TKGNNNVNSH PPCTPTYHFD RFSPNFMKES GQADPLSRIF LDAVERGDKS
     TVARCLKCSH PVNVNCTNML GRTAIQIAVD NENFEIVELL LKEPNIRIGD ALLYAVQEGV
     YRIVEMLIDH HSITKEMLGT SWSKKNNLSE ESHDFSADIS PVILASICNQ FEILQLLLSR
     GARIERPHRS NCSCSDCATM YKEDSLKYSL WRINTYRALA SPAWISLTSP DPILAAFKLS
     WELSHLASRE NEFKEVFLQL SDQCKKYACD LLDQCRSKEE VLAVLSRSSD DEDIGICDDL
     SNDGGEDGTE HVEKSALRRT TTVIHRPSRR WHGRPLYIDN SFELGDLEAT RLEPNKRLES
     QYTIVEDLAN LESHKGQMYP GNEDGVKRKG EVVGDAFETD LDGIYDGEDG VENENDFEES
     EVELETPPLR LDRLKLAIKY EQKRFVAHPH CQHILTTLWY DQLPGWRKHH PIFKLLLCVG
     FVMALPFLAL VYLVYPRGSV ARILRSPLIK FVNHSASIAI FLILLLIAST DGQSVKALES
     RQMTRGPDPN RIELLIAWWV FGFVWSEMKQ IWEEGFKAYV RQWWNWLDFI MLTLFLTTVG
     LRVVGLILRK TQRYGFDLAG REDWPPDDPT LVSEAFFAIA HIFSFARIIF LFQVNEHLGP
     LQISLGNMLI DITKFLFIFL LVITSFACGL HQLYYYYFSA DNDMRPAAFS SLLRSYQALF
     WHLFGVTQIN QYRLQTKDAE GKVVDLKSAQ VTVTVGEILL MIYHAMAIIN QADTEWKFAR
     SKLWLGYFDE GSTLPPPLNT IVSPKSIWRF GRGLIRLLTC STTFASVTDD KSKSPLYRDH
     PRHRRRYSGT VKPFPPNQAN STTGNRSLWC DHSVEPTIRL PSSVNNENSK PLASNATDTP
     AALKEENTSS KKSGKKHSYQ AITRILVRRY IHVSKKTMRQ GIVNEDDLLE IKQDISSLRY
     ELREDRQREV VRSIGHLEGL KYQLLSVLVP HHQQGQENCS TKGSSSSSSA ASRPPQPPSH
     SVGSNETASI PGIKALGAQI QALSEEIRRI SPGPNTPPLL SGLQATTATS EGLKGLKHEI
     IDEVKGELHS FARQLMQFMS QCQQPSGSNS GSETPAAPSV SANAPLSTSS LSPPRAPAPA
     SSTPSINRER IGGVSVTYRG GAAAGLSLSA PRRAQPRHQR
//
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