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Database: UniProt
Entry: W6UBE4_ECHGR
LinkDB: W6UBE4_ECHGR
Original site: W6UBE4_ECHGR 
ID   W6UBE4_ECHGR            Unreviewed;       984 AA.
AC   W6UBE4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   28-MAR-2018, entry version 11.
DE   SubName: Full=Non-lysosomal glucosylceramidase {ECO:0000313|EMBL:EUB58430.1};
GN   ORFNames=EGR_06717 {ECO:0000313|EMBL:EUB58430.1};
OS   Echinococcus granulosus (Hydatid tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB58430.1, ECO:0000313|Proteomes:UP000019149};
RN   [1] {ECO:0000313|EMBL:EUB58430.1, ECO:0000313|Proteomes:UP000019149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24013640; DOI=10.1038/ng.2757;
RA   Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA   Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA   Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA   Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y.,
RA   Wang S.;
RT   "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL   Nat. Genet. 45:1168-1175(2013).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EUB58430.1}.
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DR   EMBL; APAU02000062; EUB58430.1; -; Genomic_DNA.
DR   Proteomes; UP000019149; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR006775; GH116_catalytic.
DR   InterPro; IPR024462; GH116_N.
DR   Pfam; PF04685; DUF608; 1.
DR   Pfam; PF12215; Glyco_hydr_116N; 1.
DR   SUPFAM; SSF48208; SSF48208; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000019149};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019149}.
FT   DOMAIN       83    459       Glyco_hydr_116N. {ECO:0000259|Pfam:
FT                                PF12215}.
FT   DOMAIN      586    963       DUF608. {ECO:0000259|Pfam:PF04685}.
SQ   SEQUENCE   984 AA;  110305 MW;  B8559781E873C9C0 CRC64;
     MSVCAISYAE KTHLLPTYGW RKRFDECPPK NAGPNKLRFG ILMSNLPDIP RYIIKSQIPT
     EYRKKRLLPI DILNPLTVPS TYGVPLGGIG CGTIGRGYKG EFCRSSLIPG RFNYDVGVAD
     QFILTVWKDG TCVYHQVLST SGPAKGVQGL HSWKWSMSPQ VGNFIGLYPR SWTVYEFPEL
     KLLLICKQVS PVIPEDYKDS CLPIGVFHWT ALNFDPESDV KLSITMTWRG PRAPKRPLPP
     KVGAAGAVCA EIGHLRKHKD DEFTFPFDDS DNQLSGCLLE TFIDDMPCCF GVAAKSTDKV
     EVSRCMGFTL GCKGAGSASS KQKTTGKESY RSPWGITTHS MASAHDAISS SKLWTDLGQE
     GHLAFENTGY YVERKDKNHP LIGVAVCASF KVVAAAGGKD DLVPGQEACD FFLTWHMPRV
     HFRSALVAYR RRYVRWFSED IIRGASELLI YASRRAHLWD EAIESWQSPI LQDSRFPTWY
     KSALFNELYY IADGGTVWLD PLPAEGSAGV IAEGDGSAAS SSNGVTGGTE ELCSPLENVR
     RRNPTVRCRR PAYYSTKAPA AGDNAPADVA EIELIRARVN FGNEMGLFAY LEGHEYRLYN
     TYDVHFNASW ALLKLWPRLQ LAINYDLADM TASEDRSPMK PVFRGTHDKH RILSYALSVP
     HDCGDPEDEP WYRVNAYTLR ATDEWKDLNP KFVLMTWRDW KVTGDDDYLF YMLPLIVAIM
     EGCLEKWDKD EDGIIESANF PDQTYDMWKA VGLGAYIGSI WLAALYATKD MISYTLSKEQ
     NPVKNETLSG QEHKFGELLS KAKTNYYEKL WNGCFYRYDM HDSKANPAIM ADQICGHWLL
     RTCGAPADAI LPENTIPLTI DSVVSKNWRS VLDGEMGAIN GVRKNGKVVS NVQAEEFWVG
     TNYCLASLFI LEGMPINGFD LGGACYKTVY ENLGLQYQTP EAYTMEKGYR SPAYMRPLSI
     WSIQHSADLR HLCHNGSSPA RTTD
//
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