ID W6UNY1_ECHGR Unreviewed; 1199 AA.
AC W6UNY1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Neurexin-1-alpha {ECO:0000313|EMBL:EUB63390.1};
GN ORFNames=EGR_01881 {ECO:0000313|EMBL:EUB63390.1};
OS Echinococcus granulosus (Hydatid tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC Echinococcus granulosus group.
OX NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB63390.1, ECO:0000313|Proteomes:UP000019149};
RN [1] {ECO:0000313|EMBL:EUB63390.1, ECO:0000313|Proteomes:UP000019149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24013640; DOI=10.1038/ng.2757;
RA Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL Nat. Genet. 45:1168-1175(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUB63390.1}.
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DR EMBL; APAU02000007; EUB63390.1; -; Genomic_DNA.
DR AlphaFoldDB; W6UNY1; -.
DR STRING; 6210.W6UNY1; -.
DR EnsemblMetazoa; XM_024491130.1; XP_024354586.1; GeneID_36337596.
DR OrthoDB; 2999458at2759; -.
DR Proteomes; UP000019149; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 3.
DR SMART; SM00282; LamG; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019149};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1161..1182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..220
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 439..667
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 958..995
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
SQ SEQUENCE 1199 AA; 132357 MW; 4BD452B94448F287 CRC64;
MVELTGVIVY PFTLTCAMIL AGALKYGGPA VVLKDAKSTV EYASVSLISE TSLFIEFSGH
SLQGRLLYAE NATMGTFISL KINRPGTLRF EMKLTATNRS HQFVILSAPL DRTADQWHSA
DLRISLREKV VILFVDGKNA YPTHIEDVAA NTARYSFGGY LHVGRLPPNL LADASKVVHF
TAVMEFAFVG NIKSIFVNGR APLPLKALNG AEIAPGLSHC HLLSREVARG GDSHWLCPQN
LSCLDGLDGP KCGCNKNSRE LGICQFQSSG AKNEAFIVLL LNGSIHFRLW SPRLQKNAII
QKRQDCNSPY STCSDGTWHH LSFSYSPLRI QTEVDGDRQT FEIPKNQLRL QFKALYFGSL
APKVQERLQL QNIRNFIGCF KHIFYRSRKD FVDLIDLVKD NSTKQRQETE IGEIKCKAAA
FQTCTVARKA KRDAVSHHSA ITFVRPGGYL RSQQGWRTVS AGNITFKIRT LKTNCLLLFS
SSGWPKSEKK HVFPRDEPFH PVNPIDRLTG TDIFSAELRE GYLVFLLNTG SGINEFATEN
IWRGDQGRSG WFVADGITHY VEIHLTNGSL SVTMDGHTLS MRPRTKPKYT ILNLNGYLYV
GGLPEELRDE TPPQAWSARL REDFVGCLGA LSVDGESLDL GLEVTARWAK GYVRLGESDL
KGLSNMCTAQ ENPCGSGKCV QGSWSEPLCD CTQTNFVKNQ CKEDIKDNAT VLDSDYNCIG
VLAEDVSVYN TELETDAFIG RLSQFKLNGL DIIKIINEVA NYRSKESSYG SYDPGLLTLV
DNWKDSIEIT ASTAKDERIR TFPLHFNGDG GLMEYTLRLE ACLSIRLSLK TSMVQVCTIG
TFTLDIELDG EKLTPLGLPE GQATASRHAF ERLFLGGLPI EGAGKFRNRF RSTHEYDGCL
ADVEIVQKSV KSSLVIESNA FHPPKNPLRT AKYAKGVKLG CHLNEQSSSE GAWKTGSSPS
QCRPGVCGFG GRCVQQLDTY FCDCIMSGFR GQVCTDGSSG SHFNEVHQVY VGCDPTLISA
SVANYVGPTF VGHISGVNVN GVFLADLLMG EIISGIFYKD GKDILIDPTF TPKVRQIANL
SMTQHHQAPA IADTSSADIG GKLYPSESKE IFPPWSHDRA PQDDANRLNG VDNSASLEQL
SEAEKNGQVE ITSFLPSLNT WLLLAGFGTT LLLIALIIGY VVHKFRRRNE GSYNKQQPN
//
