ID   W6USN9_ECHGR            Unreviewed;      1422 AA.
AC   W6USN9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Putative ATP-dependent RNA helicase DHX34 {ECO:0000313|EMBL:EUB64630.1};
GN   ORFNames=EGR_00580 {ECO:0000313|EMBL:EUB64630.1};
OS   Echinococcus granulosus (Hydatid tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC   Echinococcus granulosus group.
OX   NCBI_TaxID=6210 {ECO:0000313|EMBL:EUB64630.1, ECO:0000313|Proteomes:UP000019149};
RN   [1] {ECO:0000313|EMBL:EUB64630.1, ECO:0000313|Proteomes:UP000019149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24013640; DOI=10.1038/ng.2757;
RA   Zheng H., Zhang W., Zhang L., Zhang Z., Li J., Lu G., Zhu Y., Wang Y.,
RA   Huang Y., Liu J., Kang H., Chen J., Wang L., Chen A., Yu S., Gao Z.,
RA   Jin L., Gu W., Wang Z., Zhao L., Shi B., Wen H., Lin R., Jones M.K.,
RA   Brejova B., Vinar T., Zhao G., McManus D.P., Chen Z., Zhou Y., Wang S.;
RT   "The genome of the hydatid tapeworm Echinococcus granulosus.";
RL   Nat. Genet. 45:1168-1175(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EUB64630.1}.
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DR   EMBL; APAU02000002; EUB64630.1; -; Genomic_DNA.
DR   STRING; 6210.W6USN9; -.
DR   EnsemblMetazoa; XM_024489829.1; XP_024355826.1; GeneID_36336295.
DR   OMA; CIFANSP; -.
DR   OrthoDB; 1095660at2759; -.
DR   Proteomes; UP000019149; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF148; ATP-DEPENDENT RNA HELICASE DHX34-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:EUB64630.1};
KW   Hydrolase {ECO:0000313|EMBL:EUB64630.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019149}.
FT   DOMAIN          177..344
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          439..619
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          837..876
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1009..1031
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1263..1293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1314..1346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1422 AA;  159680 MW;  4A1BB6DB84770F7B CRC64;
     MGMIASKLAV RLLRAVSAGS RMSTYDGKRL STIDFDFDIQ VHKKRLTDLF FPNSSRAPIQ
     RDSSDFPDFW KFAEKLQSFL LNQSNRSDFN HGSSRYDRVL RLNLQTRNYR LEDYMRHRMA
     EDTSHRRAIL SDRNLFAMHL IFDMYLDFLM KQRWAKIKRL HRDRENLPIA RFREPLLSKL
     MRQQVLVIAG DTGCGKSTQV PQYLADAKKT EEEVLYKRIA VTQPRKIACI SLAARVSTEM
     LREKGTKVGY QVRFERHKSK ATQILFLTEG LLLRQMQSDP FLKEYDAIVL DEVHERHWQT
     DCLLGLMKCL VVARPEVRLI LMSATINVNL FANFFNNCPI LEATFCHRDQ KSLQNGGRAG
     DGLIEFEVSA AASSIKADRL PGGGITENWK AHMCLRPLLL FVPGRLYPIT LKYCPLTPAE
     QAASLERIDP APYVRLLQHI DNTYSISERG DLLVFLSGMA EIQIVMEACK AYAEQTKRWI
     VLPLHSALPS FSQEKIFHTP PDGVRKCVLA TNIAETSVTI DGIRQAFEMI NSVVFEFVAD
     SGRVKELTWD AISRMRQLKE TTISKASADQ RKGRAGRTGP GVCFRFFKEE EYNEFQPFTT
     PEIKRVPLDL LTLQMMAMGL PDVKRFPFIE PPETKSLDEA LETLVSHGAA TRWTEGNGGN
     GERIVITPLG RLLAELPVEL SIGRVLVMAS LFRLVEPVLT LATGMAVQSP VGAARSGESR
     LRQSEALRPF ENDHGTPFMI ADLFDEWLQI KSRSAARAGL LRREDLDEAA EDRQNASAQR
     WVRRLGLEEQ RLYEMVRLRG QFLQLLRDAG LYTTGDKSGD SATVGSSHRR LLQQARHREH
     LKGKRRRMLT LQDNDDAESG RDSDAEDAEN EENGSLISAS RISRLHSWLR GRKDGRRAGD
     LGPSLEGTGL SVHDLELVLC HDLEGLSQWA DHHRRRTHGD LLLLKVVLAA GLYPQIAVPD
     PANAYRVANR GGAAGPGAEM VFHTPTKAFV VLQPNDVFVK QPDCLFPRNR DHEGLEGETT
     TNGKHPAPTS QPLRPVHKAI GSQFATDHQL LIYLDLLETT KPFLVNTIRV PALSTLLLNA
     REIDTNANAT RLVFDRWIEI ELLDPEAAQR SLAAAIWLRT SLDRLLQIKL EESQNRRLRG
     AEESGEDTLS EKKATDLPAS SIVCSTRASK RASEWRRLQR LLCEHLAAFL GQQTSGLHTL
     RKLSAVDSKN LFCASSTDGN NHASPSFPSS ESNVVRINPE KGGFQVTPFL TINSLRAFEP
     PKGKLSHGVI ADSTKDPQNS GSEVEEGGDD DATTTNLACL DLALRLHRQI ALAREAGRGG
     KPPQHSEAQT PKSEERGEDG GEFIEEDQDV NRCERCGKRL PIKPSATDLL RHKKHCKEGA
     PPIPVFESKV TFLRQNPPTT INKECTSALL YDNNDLKLDA LI
//