ID W7ABT9_9APIC Unreviewed; 758 AA.
AC W7ABT9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 08-NOV-2023, entry version 47.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=C922_03153 {ECO:0000313|EMBL:EUD66519.1};
OS Plasmodium inui San Antonio 1.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=1237626 {ECO:0000313|EMBL:EUD66519.1, ECO:0000313|Proteomes:UP000030640};
RN [1] {ECO:0000313|EMBL:EUD66519.1, ECO:0000313|Proteomes:UP000030640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=San Antonio 1 {ECO:0000313|EMBL:EUD66519.1,
RC ECO:0000313|Proteomes:UP000030640};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium inui San Antonio 1.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|RuleBase:RU004070}.
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DR EMBL; KI965471; EUD66519.1; -; Genomic_DNA.
DR RefSeq; XP_008816967.1; XM_008818745.1.
DR AlphaFoldDB; W7ABT9; -.
DR EnsemblProtists; EUD66519; EUD66519; C922_03153.
DR GeneID; 20038427; -.
DR VEuPathDB; PlasmoDB:C922_03153; -.
DR OrthoDB; 5476523at2759; -.
DR Proteomes; UP000030640; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17756; MCM5; 1.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR018525; MCM_CS.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF42; DNA REPLICATION LICENSING FACTOR MCM5; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00847; MCM_1; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW Cell cycle {ECO:0000313|EMBL:EUD66519.1};
KW Cell division {ECO:0000313|EMBL:EUD66519.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070}.
FT DOMAIN 365..570
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 758 AA; 85623 MW; A7A6628F4BC32D49 CRC64;
MLGIQEGRAF FNAARNPNNR PENNIRIEDN LPSLNEVYNY FQDFLSRYSS NTLKEGNLKR
TLFENVKNNN FTLDLKLDDI YKQQTVFENN EISATPIAER KMKKPENYSA ILARALSERP
LTYLPTVERV CYEVCETANI LNDEDEHLNY IQINLLNTFI RPTPIRGLLA ATQERFVVVP
GIIVQASKPQ HKMRKITLQC RYCDHKMSID VPLWKDKPQL PPYCRYSSTM KSSMGVANPM
DNQLGCNGVL EPYVILPNEC TFVDIQSLKM QELPEAVPTG DMPRHLQLNA TRYLCEKMIP
GDRVYVHGVL TSYNPNPKPN RADGTNFSYL HVLGFQKYDD MTGNDLNFDV EERNELTLLA
AEHDIHEKIF KSVAPELYGM DEVKKACACL LFGGTRKRIG EETKIRGDIN MLMLGDPSVA
KSQILKFVNR CAPVSVYTSG KGSSAAGLTA AVMRDSQGVF SLEGGAMVLA DGGVVCIDEF
DKMRDDDVVA IHEAMEQQTI SISKAGITTM LNSRCSVIAA ANPSFGSYDD SQDTTDQHDF
KTTILSRFDI IFLLRNKQDI EKDTLLCNHI VALHASKHKS QEGEIPLSKL TRFIQYAKKE
IAPLLSKEAR DSLRNFYVQT RAEYRGDRRS VTKKIPITLR QLESLIRLAE SFAKMELSQF
ATEKHVQMSI DLFSASTAET AKQCLIFETM SPLEQKAVKQ AEDAILGRLG KGQRASRVNL
FRELQLRGFD RSALSKALAI LIKKGELQER GDRSVRRC
//
