ID   W7FC34_PLAFA            Unreviewed;       719 AA.
AC   W7FC34;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Vacuolar protein sorting-associated protein 45 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PFAG_04689 {ECO:0000313|EMBL:EUT80049.1};
OS   Plasmodium falciparum Santa Lucia.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=478859 {ECO:0000313|EMBL:EUT80049.1};
RN   [1] {ECO:0000313|EMBL:EUT80049.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Santa Lucia {ECO:0000313|EMBL:EUT80049.1};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium falciparum Santa Lucia.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
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DR   EMBL; KE123509; EUT80049.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7FC34; -.
DR   EnsemblProtists; EUT80049; EUT80049; PFAG_04689.
DR   Proteomes; UP000030666; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.60; -; 1.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679:SF3; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 2.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 4.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136}.
SQ   SEQUENCE   719 AA;  85914 MW;  61661A7FDD11C842 CRC64;
     MENNPYVFKS LVNIYEEYLN LIIHRVKGYK VLVLDDETKS IISLIFSHSY ILEKEIFLTL
     NFNDKNIFED IYNNNNDKKE NFDFMNYKIK NLKHLKVIFL LRPTYTNILR LMSELKKPLF
     SEYYIFFTNT INDIYIEKLA KADEFDVIKN IIEYYIDTYV LHDYLFHLNI DYTSFLYKND
     HKFIDKEKKK KELNYFKQYN NNNNINSNNN YSSDGRYEKL TIEEFNKLEG NNNMIYDNNN
     NNNNINSGNI NYSHFNLSIE HINNDNRNNS NITLYMNQIV QRIIDGLFSF LCCIRQVPDV
     IYNRHSKICK HIIDMLKEKM LRHQSVFNNI LDIYEKYNDE MERKKKKKIL ETNNEPNYQF
     NHLINQNIHE ITEGDACYFL ILDRNEDPIT PLLTQWTYQS MLHELIGIEN NKINLNCNNK
     EEEQQQIVMS CNYDDFYNEH LFDNFGDLGQ AVKNYVDIYQ EETSKKTNLE SIDDIQKFID
     IYPNYKKLSG NVTKHVNILH KFSDIVQKRQ LFYISELEQS IACYHTKNDH FKQVIDTIKN
     YTYTNYDVLR LSLLYSLKYA DEQHINVIKN ELAKRNIQKD QILLIDALLL YSSQQTKYNQ
     LFKEQTFLNL AKTTITRTIK GTSNVFTLHK SYLYYLLEDI IKYKINTQLY TTTNLLHTEP
     TLNKKINSIV VFFIGGATYE EYRDVQHLSK KYNISIVLGS THMHNSQSFL ADVLQLIKK
//