ID W7FGY2_PLAF8 Unreviewed; 1997 AA.
AC W7FGY2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EUR75554.1};
GN ORFNames=PFBG_01296 {ECO:0000313|EMBL:EUR75554.1};
OS Plasmodium falciparum (isolate 7G8).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57266 {ECO:0000313|EMBL:EUR75554.1, ECO:0000313|Proteomes:UP000030688};
RN [1] {ECO:0000313|Proteomes:UP000030688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7G8 {ECO:0000313|Proteomes:UP000030688};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Daily J.P., Sarr O., Ndiaye D., Ndir O., Mboup S., Lukens A.,
RA Stange-Thomann N., Mauceli E., Gnerre S., Jaffe D., Zainoun J.,
RA Wiegand R.C., Birren B., Galagan J., Lander E., Wirth D.F.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EUR75554.1, ECO:0000313|Proteomes:UP000030688}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7G8 {ECO:0000313|EMBL:EUR75554.1,
RC ECO:0000313|Proteomes:UP000030688};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum 7G8.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
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DR EMBL; KE123596; EUR75554.1; -; Genomic_DNA.
DR EnsemblProtists; EUR75554; EUR75554; PFBG_01296.
DR Proteomes; UP000030688; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR PANTHER; PTHR18867; RAD50; 1.
DR Pfam; PF13304; AAA_21; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..240
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT DOMAIN 1764..1968
FT /note="ATPase AAA-type core"
FT /evidence="ECO:0000259|Pfam:PF13304"
FT REGION 1661..1690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 561..588
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1543..1573
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1731..1762
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1997 AA; 238703 MW; 7B5724F938B934EE CRC64;
MTTLEKIGIQ GIRSYNDEDV EILEFATPIT IIYGNNGSGK STIIECLKVS CTGDFPPNAE
KGKSFLHDPL ISNKMNIRGK IDVLLNNYNN KRIGISRSYN LFYSKDKNKK VKHTFRALDN
NIIIKKEKGD DLIITNKCVD INNHIPKLMG VSKALLENVI FCHHDENLWP FSESIKIKKK
FDELFGDDHF SKILEELLKC KKYLNDLLKR KEFDLIHIKE NFEKKKNIYI EIEKNEKEIQ
SAQICIQLDV EEIEENTIIL NNLIKKKNLL YKLIGNIDSY FLLYTKFKVD AEAYKDLKEV
YEENYTELLY FQEVFNNDIN KCEICIQKVK QDIQNLQHEK DTCMFNYNES NKYDDNYELS
KKQLNEYIIK RDDIRNKLKD IFFYNDQIFF SNYKGNSSSD MIKHSSINEG HQKEKLKKKF
KKHDSVYIKD HLLKEYENLL HMYDIHKEDI ALYNHDVMLS YKNEEHIPSN ARNNNNNHFD
DDNKNKCDDK KFIEIPNVSN ILSNVPYLKK KHEKKINSIR YILKRHISHI KRNKYKKRNV
IYKIKNYKKR LLKIEKNITL LDIYKNKLNK LKSNEIIYEQ NLKKIEKLNQ LKCLYDNLTT
LDNEMDTYNI QKENNYYEEQ IEKNMKQIND IQKLKIWIHT FCNIIRNYNI FYEFIQRCKK
IHEHCVIFFD ILFSLLDVIK TDFYKIVDML KERDMDLYYY IERGMQKKIN VERNVCVERN
VCVENNICVE KNICVEKNIC VEKNICGEKK KITKLKSNIE IEESVEKIKD NKINECDVNV
DTLNKTNSIH HVNNIKINSK SLVCMNEHLQ RKRENEKLND YTCKLKKQKT HLDISILKNR
KYLDILLNII NIFIDKYENK INNIKTLIIP LNQKVLEISK KLNNMNNNIN EYKNYLSNFI
HMLKEKKYKD VKDFVNYVEA IDNQIKIKKK NLWMLNGKED LMNEFKNHLK SDEQNNSDNN
KKVGVEKKKK KNCLFCKNTI SQNNKDIVQI EMYIEEQKRD MLKKIEESEK DINILKNKKE
ENIILLNYYY YHIKHIHTYT NDSNEMIVKL KEELLSAQDS IEKYNIKIKN IHRKFQLVQK
FKETCVYLIN IQKDILDVEK YIKDESIKIK GNFQEMKNKI KDNVENNKMS NNTNKCNDTK
TCNNTKTCNN TYTCDHLFIE KLYHMIENLD ISIEVKESNL LKNIKEFVKK FAKYNNKDII
NIFYNKICTS NVNDSYSYIP YNDIINVDLY QQYNYQNNYK DRFKYNLYKI NNANYICKLL
SPHQKVSLKD CYSSDQTPQK IYEEKKVDDD HHSYNKSKSL IENYITPCKN KEESVKEPNM
CSIKHIYDNG SSNDDILNND KTVLLNKINS SYLSFVLNIG TSYYSNEEIK ENNKNDTNKM
YDNINQNTYG TFLKCSDFLH NLPSIILNNK HFEKMYRNFL SYLNVEEYTR KEQNKMIEKM
KVVIKDRRAY VIKKSKVLEK TINIDKRIRD LIKKMDIYIL YYKEKKKKII DEKINVKNLL
IEQRDTQLKY IKRCIRNNKK SIFLEKRNYY LKMNMIYILI KKLKHTEEEI VNKEKYLKDV
KEKLNNNEII KNQVICIDKK INEKKEHILC LEKEKINIEK MLHNIIMNTN MKKMYEQFLE
HHQTFILSLN QLKASFFLYE RKNIKNSNMC KLEYKDEING DKKKENDNTV SSNNDSIINN
DNRNKKNRYN DEENGINYIN DIVKKLEENY NNNTNIYNFI NKTFDITDCL KNRLKDIIKI
EEDDLNEQIE KYTKSITALK IKEAEMNGKI CLRKEYLEKL KEDIKSETLI NIDKEYKKKI
IEIFVYKNLI KDLQNFHFSF DQAIIKFHSL KMQEINLSIK NLWRRVYNSA DIDYIYIKSD
IQTEPTDKSS QRRSYNYRVV MVKDNCELDM KGRCSSGQKV LSSIIIRLAL AESFSIKCGI
LALDEPTTNL DKANSRNLAS LLANIVELRK SSSSFQLILI THDNYFVDIL SQYGLTNCFY
KIKKNNLGYS KIERVNT
//
