ID W7G3E8_PLAFA Unreviewed; 2178 AA.
AC W7G3E8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Chromo domain-containing protein {ECO:0000259|PROSITE:PS50013};
GN ORFNames=PFAG_03528 {ECO:0000313|EMBL:EUT83653.1};
OS Plasmodium falciparum Santa Lucia.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=478859 {ECO:0000313|EMBL:EUT83653.1};
RN [1] {ECO:0000313|EMBL:EUT83653.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Santa Lucia {ECO:0000313|EMBL:EUT83653.1};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Santa Lucia.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE123502; EUT83653.1; -; Genomic_DNA.
DR EnsemblProtists; EUT83653; EUT83653; PFAG_03528.
DR Proteomes; UP000030666; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR023779; Chromodomain_CS.
DR PANTHER; PTHR24329:SF580; DORSAL ROOT GANGLIA HOMEOBOX; 1.
DR PANTHER; PTHR24329; HOMEOBOX PROTEIN ARISTALESS; 1.
DR Pfam; PF00385; Chromo; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS00598; CHROMO_1; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2154..2174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..126
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 432..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 752..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1054..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1168..1202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1295..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1447..1484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1517..1600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1804..1937
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2030..2053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2111..2147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 761..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..904
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1195
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1304..1320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1517..1536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1563..1578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1814..1892
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1893..1913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1914..1937
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2030..2044
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2111..2141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2178 AA; 256558 MW; 453C879FD6765FAE CRC64;
MVLKRGKGNS HKSRKRKRFK DEINEDFNFE DNFRIVGEPD FNEVFEVEKI IMARYKLNCK
RKKNRKDENL DDFEFYIKWK NYDSDENTWE PFENLSPNLK GQARKVALQL TEEIDNCNKN
KNEKNDNEGE NIEETVVGDN INRYIEGNII NNMENNSQQN IEQYNNKVYE QTRLVQNTDV
LNPNKNKMGF IEIKPNDIDD DDEEIINIMR ELEAENMKKE KNKLRNRNFS LFNMSSNSRL
SNEINSYLYE NSHKMDVTYI GKKKTGNIKS ILSLTNRINN DDNNNNNNNN IYNNNIYNKR
NYNNNYNHCK YSTDLSYDGN NNSVHLNDLH HLNDEEKNNL LFLYDSDDLI KKDSRIANDI
HYNNLFLSKS IKKLRNKYLE SLLNNNINNK NIFDDESLLK MNLGLSQPSN LCLNNNEKSK
KCQKPHTFVN TVKNSNKNNE NIINDFNKEK DESSQNDTSF LYSTDRTSTN DYYITRKEKI
KPLQKESIIN NEEDNVQEHH KLLLDKNGNN NNDDDNSTDD NNNDDNKNNN DNKNNDDNKN
NDDNDNNDNN NNNNNNNNNN NNSNGDNNNN NNNNGDNCNN NNNNGDNCNN NNSNNNNNNN
HRINNKLDSF EDNNYRENYI FNYLNEKDKT DDHNSNSYDN SNSNSNMFNY NSNINIDEQN
KNIAKNNGDL KNIKRNVLNK NKGTKFLPSY NTCFKKQICN LRKNMKKKLI VNSMSNKFNI
SQVNANNENN FEEFKQFCLQ NGNDQTRKKR LQHEKKKSTN SKNSINNNNN NYYDYNHYFN
NKKRSEDDNS FEFNDSYFTN SANTIDQVSK LVQKYLALPS NENIMATDYL LNTTTNNNDN
NKNNDNINNE DNNKNNDNIN NDDNNNNDDD NNNNDDDNNN NDDNNKNNDD NNKNNDDKNI
CKKGRKTNNI KKRKILVNDN NISLGNYSNN EYYDYHDVNN NSNSNIRNMI HNKSLSDFID
EDKIFKQKSG KNIVKNLFCN KKSYSNNSAY VNRGISEYAE ENIGDKNFIN NQKCNNYFLN
LKELQNIYAS EKYGKSKKGN KNLVSKKIND YIYNNNSGNN SSNNNSSNNR NNNIRKSYIN
KLTESEYDSV YETLINRYCK NTTNKYSKKI NNDENGNTNE PINDIKYYIN DNNNNSTSNS
RPSLIHDNLS ENDFNKIGDE LKRKQSQITK ENQKYDAHVD DDIDDDEEEE EEENTDKNNN
TIRSSIQSDI IYKILNDEKS KSQEQNVHIL NKDNINEFSE FKKKDGENDE MVFFSSDNMK
SNIYVAKKNY SSESFNNKHI MKKTQHLYNM DEIKNKNKNK SKNVSDSTNE NNHTNHNNNI
NKYDGLNSMT INIKDILDTK NDKRDYYINV LENVLSALKE NRTYNSKDLN ISKENENANG
HIRSNSYTDT SSILLNRKIP EISGEKENYE NLRNLKRRTF HNDSIEYSRT PKRVLFEINK
EDHQNKKLKN KNLIDDKVGD DDDDNNNNNN NNKSDDSKTN DDNKIKKNKT VFSIYSSIKN
KSRNILSNIK LGHFLTNKNK SQNNKTDESQ NQNVVPIRIK KEKEDDELEE NAENEVSNDK
HNMNNDEQNN SGGVNKMRSE QDHINDDDNN INSYDDESDV NFNNKKNDYK GKRIFSRLEI
LNINIVKLNY LDKLGEYIDS VDKLAIGNLD SLLKNFNILN NYKGKDKVMI YFLNPGFQKR
LLEAYSNIFL HFDIFIDNKT YNFIFNNCEY VNVLLYRAFS IKREDEYNRL RNIPSYELSK
YLYLFYELGK MTEKLNTLFK ILFIPTQVKP HKYYFPSVEY FERFYIHLHY KTRADDVDVD
TNQVGGEKLE EEKLEEEKLE EEKLEEEKLE EEKLEEEKLE EEKLEEEKLE EEKLEEEKLE
DENVEDENVE EEKLEEEKLE EEKLEEEKLE EEKLEDEKLQ EENMENKQIE DEKLEDEQIE
DEKLEDEQIE DEKLEDEQIE DEKLEEENME NKEIEDEKLR NEQNLSNEYN NTANIIKKDN
IFEKNINEEY NIKILEDKTE YIINNEYLKN SPGDVSNFED SMNEEGCNKS SIENNNIDNK
NGLQNNNVEE KDENNHEKNN IYINKIDHNI NNCINNGGVL TDNDIENIDY IKKDFNNNLS
TYSNSSTIIQ NNNIHNEDSD DCNNNNNNNN NNSNSNNNND DDNNNNDDDN NNNIIIMMMI
IIIMMMIIII IILLKTYL
//
