ID W7IIL9_9PSEU Unreviewed; 492 AA.
AC W7IIL9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=UO65_4137 {ECO:0000313|EMBL:EWC60565.1};
OS Actinokineospora spheciospongiae.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC60565.1, ECO:0000313|Proteomes:UP000019277};
RN [1] {ECO:0000313|EMBL:EWC60565.1, ECO:0000313|Proteomes:UP000019277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EG49 {ECO:0000313|EMBL:EWC60565.1,
RC ECO:0000313|Proteomes:UP000019277};
RX PubMed=24604655;
RA Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA Hentschel U.;
RT "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT Bacterium Actinokineospora sp. Strain EG49.";
RL Genome Announc. 2:e00160-14(2014).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWC60565.1}.
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DR EMBL; AYXG01000153; EWC60565.1; -; Genomic_DNA.
DR AlphaFoldDB; W7IIL9; -.
DR STRING; 909613.UO65_4137; -.
DR PATRIC; fig|909613.9.peg.4139; -.
DR eggNOG; COG1012; Bacteria.
DR Proteomes; UP000019277; Unassembled WGS sequence.
DR GO; GO:0036243; F:succinate-semialdehyde dehydrogenase (NADP+) activity; IEA:RHEA.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07099; ALDH_DDALDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000019277}.
FT DOMAIN 3..455
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 236
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 270
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 492 AA; 51806 MW; 10C87EA5D154C3CF CRC64;
MQSKQTTFES LNPATDEVVG THPVHTAEEV RAAVRRAETA AAWWESLGFA GRAERLQRWK
GTMTRRAAQL ADVVHAETGK PHADAMLEII LAIDHTAWAA KNAKKVLGPH RRSPGLLMSN
QAASVEYHPL GVVGVIGPWN YPVFTPMGSI AYALAAGNAV VFKPSEYTPG VGEWLVRTFA
EAVPEQPVLQ LVTGYGETGA ALCRAGVAKI AFTGSPATGR KIMAACAETL TPVLIEAGGK
DAMLVDADAD VDAAADGAVW GGMSNAGQTC TGIERVYVHE KVYDRFVAAV TEKAGAVRPG
YDDSAAIGPI TMPAQLAIIR RHITEALAAG GRAVVGGADS VGDKYVQPTV LVDVPEDASA
VREETFGPTL TIAKVRDMDE AVAKANDSKY GLGGSVFAKA RGMELARKLR SGMTSVNSVI
SFAGVPSLPF GGSGDSGFGR IHGPEGLREF GRAKAITRQR FTAPLTLTSF ARGAKVDAQV
AKLITLLHGR RR
//
