ID   W7IRY3_9PSEU            Unreviewed;       584 AA.
AC   W7IRY3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Beta-lactamase (Cephalosporinase) {ECO:0000313|EMBL:EWC59487.1};
DE            EC=3.5.2.6 {ECO:0000313|EMBL:EWC59487.1};
GN   ORFNames=UO65_5215 {ECO:0000313|EMBL:EWC59487.1};
OS   Actinokineospora spheciospongiae.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC59487.1, ECO:0000313|Proteomes:UP000019277};
RN   [1] {ECO:0000313|EMBL:EWC59487.1, ECO:0000313|Proteomes:UP000019277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EG49 {ECO:0000313|EMBL:EWC59487.1,
RC   ECO:0000313|Proteomes:UP000019277};
RX   PubMed=24604655;
RA   Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA   Hentschel U.;
RT   "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT   Bacterium Actinokineospora sp. Strain EG49.";
RL   Genome Announc. 2:e00160-14(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWC59487.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AYXG01000203; EWC59487.1; -; Genomic_DNA.
DR   RefSeq; WP_035287253.1; NZ_AYXG01000203.1.
DR   AlphaFoldDB; W7IRY3; -.
DR   STRING; 909613.UO65_5215; -.
DR   PATRIC; fig|909613.9.peg.5212; -.
DR   eggNOG; COG1680; Bacteria.
DR   OrthoDB; 9809635at2; -.
DR   Proteomes; UP000019277; Unassembled WGS sequence.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR001466; Beta-lactam-related.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   PANTHER; PTHR43283:SF11; BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43283; BETA-LACTAMASE-RELATED; 1.
DR   Pfam; PF00144; Beta-lactamase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EWC59487.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..584
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039703929"
FT   DOMAIN          90..418
FT                   /note="Beta-lactamase-related"
FT                   /evidence="ECO:0000259|Pfam:PF00144"
SQ   SEQUENCE   584 AA;  62174 MW;  CE6289F65A2B7392 CRC64;
     MAWRTRGGAA VLCLALVAAT VAGSAVAVAA HPGDERAAGR FDLPQRGFAP ADTVLRPGTP
     ESVGLDPAPI RAAGEAIAAW TGPSPTTPLF PGAVSLLVHH GTVVHRQAVG KALRYADGAG
     TELPAEQQVP VRADTVFDLA SVSKLFTSLA VMCLVEDGRL KVDRRVAGYL PEFGVNGKEQ
     ITVRQLLTHT SGLEPFIPLW RDWPDEPSRV KAVMDRAPVN PPGSSYVYSD LNLITLGVLV
     ERLSGRSLDA FVADRITRPL GLVDTGYNPP ASKLDRVAAT EFQSAPPRGV VRGQVHDENA
     WSLGGVAGHA GVFSTAADLA VLGQAILNGG SYAGRRVLRP DTVHTMLTNF NGDFPGNDHG
     LGFELDQRWY MGGLSGPRTA GHTGFTGTSL VIDPASRSIA ILLTNRVHPS RNRGTINMAR
     ERLASGLASA MAVHPRHGPD AWFAPPVDAT TATLTTPPLT SRGAMRVRFD AFVDTEDTDP
     LALESSADGQ TWRRIPLRAW GTGAPVGQTE LLAGSGHRSW WTVDAIVPGG DGITLRWVST
     TDSRYTGRGI LLDGIVVTDG DRMLLNGEKE PHLMRPLGWR LQTR
//