ID   W7IT98_9PSEU            Unreviewed;       677 AA.
AC   W7IT98;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Mg-protoporphyrin IX chelatase {ECO:0000256|ARBA:ARBA00030759};
GN   ORFNames=UO65_0547 {ECO:0000313|EMBL:EWC64115.1};
OS   Actinokineospora spheciospongiae.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC64115.1, ECO:0000313|Proteomes:UP000019277};
RN   [1] {ECO:0000313|EMBL:EWC64115.1, ECO:0000313|Proteomes:UP000019277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EG49 {ECO:0000313|EMBL:EWC64115.1,
RC   ECO:0000313|Proteomes:UP000019277};
RX   PubMed=24604655;
RA   Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA   Hentschel U.;
RT   "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT   Bacterium Actinokineospora sp. Strain EG49.";
RL   Genome Announc. 2:e00160-14(2014).
CC   -!- SIMILARITY: Belongs to the Mg-chelatase subunits D/I family.
CC       {ECO:0000256|ARBA:ARBA00005799}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWC64115.1}.
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DR   EMBL; AYXG01000021; EWC64115.1; -; Genomic_DNA.
DR   RefSeq; WP_035278390.1; NZ_AYXG01000021.1.
DR   AlphaFoldDB; W7IT98; -.
DR   STRING; 909613.UO65_0547; -.
DR   PATRIC; fig|909613.9.peg.562; -.
DR   eggNOG; COG1239; Bacteria.
DR   eggNOG; COG1240; Bacteria.
DR   OrthoDB; 9775079at2; -.
DR   Proteomes; UP000019277; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd01451; vWA_Magnesium_chelatase; 1.
DR   Gene3D; 1.10.8.80; Magnesium chelatase subunit I, C-Terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041702; BchD/ChlD_VWA.
DR   InterPro; IPR041628; ChlI/MoxR_AAA_lid.
DR   InterPro; IPR000523; Mg_chelatse_chII-like_cat_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR35023; CHELATASE-RELATED; 1.
DR   PANTHER; PTHR35023:SF1; MG-PROTOPORPHYRIN IX CHELATASE; 1.
DR   Pfam; PF17863; AAA_lid_2; 1.
DR   Pfam; PF01078; Mg_chelatase; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019277}.
FT   DOMAIN          493..633
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          334..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        334..353
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   677 AA;  69794 MW;  7C90FE32C81B986C CRC64;
     MPSPAGFPFS AVVGHADLRL SLLLNAVHPA IGGVLVRGEK GTAKSTVVRA LAALLPALAV
     VEGCRFGCDP AAPDPGCPDG PHLEPDAASR PARLVELPVG ATEDRLIGSL DLERALTEGV
     RAYQPGLLAA AHRGVLYVDE VNLLHDHLVD LLLDAAAMGR AHVEREGVSV AHAASFLLVG
     TMNPEEGELR PQLLDRFGLT VEVRAARDVD TRTEVIRRRL AFEADPAGFA AGWAAADADL
     AARIAAARAA LPGVALPDAE LRRIAAVCAA FDVDGMRADL VLARAAIAHA AWRGADAVTE
     EDVAVAARLA LPHRRRRDPF DEPGIEQDQL DQALRDAAEQ TGEPERTDPD PDPDPGPDGP
     GGGAPDPGDG PADDSGQSDS PPPDGPAPEG QDTQPKGKGG GTQAPATPDP AFTARLLQVD
     GVGEGAPGRR SRSRAGSGRA LRAATSQGSG IHLVGTMTAA APMQLVRGRS GPGLVVRPDD
     VRRAVREGRE SNLVLFVVDA SGSMAARKRM SAVTGAVISL LRDAYQRRDK VGLVTFRGPG
     AEVALPPTSS VEAAVARLRA LRTGGRTPLA DGLLRARELL RVERLRDPRR RALLVVVTDG
     RATVAARPGG DAVADAVRAA GLVAADGVAS VVVDCESGPV RLGLAGRVSA ALGGTGLRLE
     ELSADAVAGV VRAARAA
//