ID   W7J1Q3_9PSEU            Unreviewed;       519 AA.
AC   W7J1Q3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Acetyl-coenzyme A carboxyl transferase alpha chain {ECO:0000313|EMBL:EWC62977.1};
DE            EC=6.4.1.2 {ECO:0000313|EMBL:EWC62977.1};
DE            EC=6.4.1.3 {ECO:0000313|EMBL:EWC62977.1};
GN   ORFNames=UO65_1687 {ECO:0000313|EMBL:EWC62977.1};
OS   Actinokineospora spheciospongiae.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=909613 {ECO:0000313|EMBL:EWC62977.1, ECO:0000313|Proteomes:UP000019277};
RN   [1] {ECO:0000313|EMBL:EWC62977.1, ECO:0000313|Proteomes:UP000019277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EG49 {ECO:0000313|EMBL:EWC62977.1,
RC   ECO:0000313|Proteomes:UP000019277};
RX   PubMed=24604655;
RA   Harjes J., Ryu T., Abdelmohsen U.R., Moitinho-Silva L., Horn H., Ravasi T.,
RA   Hentschel U.;
RT   "Draft Genome Sequence of the Antitrypanosomally Active Sponge-Associated
RT   Bacterium Actinokineospora sp. Strain EG49.";
RL   Genome Announc. 2:e00160-14(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWC62977.1}.
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DR   EMBL; AYXG01000060; EWC62977.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7J1Q3; -.
DR   STRING; 909613.UO65_1687; -.
DR   PATRIC; fig|909613.9.peg.1699; -.
DR   eggNOG; COG4799; Bacteria.
DR   OrthoDB; 9803706at2; -.
DR   Proteomes; UP000019277; Unassembled WGS sequence.
DR   GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004658; F:propionyl-CoA carboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   InterPro; IPR034733; AcCoA_carboxyl_beta.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR011763; COA_CT_C.
DR   InterPro; IPR011762; COA_CT_N.
DR   PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR   PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR   Pfam; PF01039; Carboxyl_trans; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 2.
DR   PROSITE; PS50989; COA_CT_CTER; 1.
DR   PROSITE; PS50980; COA_CT_NTER; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EWC62977.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019277};
KW   Transferase {ECO:0000313|EMBL:EWC62977.1}.
FT   DOMAIN          1..262
FT                   /note="CoA carboxyltransferase N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50980"
FT   DOMAIN          266..515
FT                   /note="CoA carboxyltransferase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50989"
SQ   SEQUENCE   519 AA;  55676 MW;  A8E9B2995F9ED50A CRC64;
     MKEHTVLHQI EELTALKAEV RRGPSERATA AQHAKGKLTA RERIDLLLDE GSFTEVEPLR
     RHRAVGFGME DRRPHTDGVI TGWGEVEGRT VFVYAHDFRV FGGALGEAHA QKIHKVMDLA
     EAAGAPLVSL NDGAGARIQE GVQALAGYGG IFQRNTRASG VIPQISVMLG PCAGGAAYSP
     ALTDFVFMVR GTSQMFITGP DVVRAVTGEE ITQDGLGGAD VHATGSGVAH FTYDDERECL
     ADVRHLLSML PANNRELPPV LRGDDPPDRP TDVLAEIVPA DQGRAYDVRR VIEEVVDDGD
     FLEVHPGWAG NLVCALARLD GGLVGVVANN PAVLAGALDI EASEKGARFV QWCDAFNVPL
     VTLVDVPGFL PGVSQEHSGI IRRGAKLLYA YCNATVPRVS LVLRKAYGGA YIVMDSRSIG
     ADLALAWPGN EIAVMGAEGA ANVVFRREIA EADDPAAVRA QRIKEYRAEL MHPYHAAERG
     LVDDVIAPGE TRSVLVRALA MLRAKHAALP ERKHGNPPQ
//