ID   W7JDX2_PLAFA            Unreviewed;       681 AA.
AC   W7JDX2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Heat shock 70 kDa protein {ECO:0000256|ARBA:ARBA00018181};
GN   ORFNames=C923_02236 {ECO:0000313|EMBL:EWC77090.1};
OS   Plasmodium falciparum UGT5.1.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=1237627 {ECO:0000313|EMBL:EWC77090.1, ECO:0000313|Proteomes:UP000030697};
RN   [1] {ECO:0000313|EMBL:EWC77090.1, ECO:0000313|Proteomes:UP000030697}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UGT5.1 {ECO:0000313|EMBL:EWC77090.1,
RC   ECO:0000313|Proteomes:UP000030697};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium falciparum UGT5.1.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR   EMBL; KE124531; EWC77090.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7JDX2; -.
DR   SMR; W7JDX2; -.
DR   EnsemblProtists; EWC77090; EWC77090; C923_02236.
DR   Proteomes; UP000030697; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10233; HSPA1-2_6-8-like_NBD; 1.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003322};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030697}.
FT   REGION          653..681
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          266..293
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   681 AA;  74257 MW;  586FBDD254C2189A CRC64;
     MASAKGSKPN LPESNIAIGI DLGTTYSCVG VWRNENVDII ANDQGNRTTP SYVAFTDTER
     LIGDAAKNQV ARNPENTVFD AKRLIGRKFT ESSVQSDMKH WPFTVKSGVD EKPMIEVTYQ
     GEKKLFHPEE ISSMVLQKMK ENAEAFLGKS IKNAVITVPA YFNDSQRQAT KDAGTIAGLN
     VMRIINEPTA AAIAYGLHKK GKGEKNILIF DLGGGTFDVS LLTIEDGIFE VKATAGDTHL
     GGEDFDNRLV NFCVEDFKRK NRGKDLSKNS RALRRLRTQC ERAKRTLSSS TQATIEIDSL
     FEGIDYSVTV SRARFEELCI DYFRDTLIPV EKVLKDAMMD KKSVHEVVLV GGSTRIPKIQ
     TLIKEFFNGK EACRSINPDE AVAYGAAVQA AILSGDQSNA VQDLLLLDVC SLSLGLETAG
     GVMTKLIERN TTIPAKKSQI FTTYADNQPG VLIQVYEGER ALTKDNNLLG KFHLDGIPPA
     PRKVPQIEVT FDIDANGILN VTAVEKSTGK QNHITITNDK GRLSQDEIDR MVNDAEKYKA
     EDEENRKRIE ARNSLENYCY GVKSSLEDQK IKEKLQPAEI ETCMKTITTI LEWLEKNQLA
     GKDEYEAKQK EAESVCAPIM SKIYQDAAGA AGGMPGGMPG GMPGGMPGGM PGGMNFPGGM
     PGAGMPGNAP AGSGPTVEEV D
//