ID W7JFP9_PLAFA Unreviewed; 2032 AA.
AC W7JFP9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
GN ORFNames=C923_01476 {ECO:0000313|EMBL:EWC77870.1};
OS Plasmodium falciparum UGT5.1.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1237627 {ECO:0000313|EMBL:EWC77870.1, ECO:0000313|Proteomes:UP000030697};
RN [1] {ECO:0000313|EMBL:EWC77870.1, ECO:0000313|Proteomes:UP000030697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UGT5.1 {ECO:0000313|EMBL:EWC77870.1,
RC ECO:0000313|Proteomes:UP000030697};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum UGT5.1.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KE124470; EWC77870.1; -; Genomic_DNA.
DR EnsemblProtists; EWC77870; EWC77870; C923_01476.
DR Proteomes; UP000030697; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd14938; MYSc_Myo24B; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF706; MYOSIN-11; 1.
DR Pfam; PF00063; Myosin_head; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000030697}.
FT DOMAIN 77..900
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1000..1019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1242..1276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1432..1462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1286..1322
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1354..1381
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1530..1587
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1444..1458
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 185..192
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 2032 AA; 240897 MW; 513C8EB1CBB201C4 CRC64;
MINPEEQQFK EGDLVWCNKI PSTCEEEDVL YILCRIIEKK SEDHIILTKY DNETNGSTFV
CESKHLYNAN NNNPFSLDED DMIKLKHFNE PTVLYHLHGR YEKNIFFTKM GPLLIYVNPM
EKEKNYENNT LNKINNINDI CNDVIEKYKY SHSSDDIKLN EYHVGMSALK YMNVLKKNQS
IIITGESGSG KSKIFNSLLN FFSNERIFPL KKKFEIRNDD NINISEILKH GNIIMEALGN
AKTSKNNNCN RYAKYCILQM DKDKIKHIYM KKFLFDKERL INRRSDENNF HIFYYILNGS
SENFKKKYFL KNLEDYNIFK NDSIRDNSND EQNFIQLLTS LNILFDDDKK QIDFFFSILS
AILLLGNIQM IKSPKKSLFR QNFICEFPSN YKQLQEQLEF LDESHIWDMS KKSSSSSSYD
EGSSNLSNMD SSEYLDKNTY IFLVASKLLG IDAETFLKYF TSGYLLNEII LMKGQNEMKV
QKKIERFMKT CYEELLNWVI CKITTKYNDN LINNKEKEII QNNEIFENEK SEKNDNYINI
LDIIYFENLK ENSLEQFLIN TTNEFILKVY TDFYYKKREN IYKQEGLELS CDSIYIDNEQ
LYKILISKEG SLFSLLENIC TKKSFDKSNL CSTIVNRFIK NPYIKANSLE VNKAFIIIHS
YSQISYKTEH FIEKNVDILT RGFIEMIKKS DNKYMQQFCS SYDYDTNGKI MEENKRFSVH
TNFKLFKKEY DPNNQMAVTL LRNNLLELTN SIEKSFCHFI MCINTCRKKI NTEMVPHFDK
KLVLSQVTNF HMMIEADQFK DEYFPHMFSF FEFVQIFKCL KNYKKINHEG DDIHVHENVN
NMENMYHTNN PFDNVESNDN KTVCEQILGY MKIGEKNWTI GKNMIFLNEK SMNILVDSVY
YMWLNSLENE SGKEELCDLK EMMKENDKGE KYEKRELEYI NLDYENVEIQ MENDQSYLNC
DNKNVDTIKE MEVEIKIGSY NTELNNKMVD HDIVDNKYDR DDNVHRKSST NMSYDDNQNM
EGGLLKVNLK KGDNTSLSDM EEEYVNVNVN VNDEEEKMRR MSKEKDRKGS KVKRKSSLLR
LSTSLRNSFQ KMKKSKLNEK EEKVGEKVEE KVGVKVEENV GVKVDEKIGV KVEEKVGVKV
DEKIGVKVEE NVGENVSENV GENVSENVGE NVDEKVCEEK DDGYGVMNFF NNINFYKKGL
KELNNAIKNF NPINGKLKKD KFFNMGIQNF YNKKKNFFLD SKRGSDASKK GEENKDEQEN
KNEEDNIDVK DNKDNLDVED NLINVKESKD TEVQNDEQKI DKNNEEDIKD NVIEDMNKEQ
NNYNKMFKVE DNIIDLDYVD LSNLEKCMNE EDTNNMDEDE KNNMKDDINE EQNNIDEIYK
SDDHVVNLDN TKKDVNNNDK SNVTEELENM NYMKTKTEDD KREDMEICEV KENKPDDNQI
NNVQKKKKKK KRRKKKKKSV LNNVEDKNMF DNDVSVEKDM MEKDISDEKY MMDDDNNMMS
PDNVTNVNKD ILNIEKVMIY DYHNVPDDDN MMSEKKMDNM ENEYEKIKEE KIDEIEIEYD
KIKEENIDEI ESEYDNIKEE YIDEIELDNK ENVEDEKEEE CVEETKIRDD EIYYDKMGDM
EKNKSTSNIG IELYDNEKNS DDSCVHNEDS NNLTKCDEED CLDENTKDCY DDYMDENYID
FDFSCVKAIT LNKLGNMNEL SCYKNDENDI IQTLFDYYDC SYDKAYENCF FENRWDDIVE
EDDSFIFLNV YNNKEMSNLR NSENKDMLLN HLNDIYICKN NEKQHVMKII KRMKNAMEKV
HGNNKWNILF SFSDCCIRSF IHDKDNVHIE KNVDLLKEKI LFYNEEYCIY NNKENELNEY
TYNPIVEYVA LPRNKEVHEI CISNNIHKNF IKNNYKIMCF QPTKISYKDF LKSKLFYKSI
NYTNFQTQNI TQVTIDFSYM DDKMKNNFKQ HVINEFVNNP NITKEDLSNS LFHLATYFYH
EKNKEPGTWC VFISEEKGFA GAVNIVKNKY LRMTAQNKNK KYNILVFKTP AL
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