ID W7JM69_PLAFO Unreviewed; 2352 AA.
AC W7JM69;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Translation initiation factor beta propellor-like domain-containing protein {ECO:0000259|Pfam:PF08662};
GN ORFNames=PFNF54_05463 {ECO:0000313|EMBL:EWC85796.1};
OS Plasmodium falciparum (isolate NF54).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC85796.1, ECO:0000313|Proteomes:UP000030673};
RN [1] {ECO:0000313|EMBL:EWC85796.1, ECO:0000313|Proteomes:UP000030673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:EWC85796.1,
RC ECO:0000313|Proteomes:UP000030673};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum NF54.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE123882; EWC85796.1; -; Genomic_DNA.
DR EnsemblProtists; EWC85796; EWC85796; PFNF54_05463.
DR OMA; PMNSINN; -.
DR Proteomes; UP000030673; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR011387; TIF2A.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR PANTHER; PTHR13227; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR PANTHER; PTHR13227:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR Pfam; PF08662; eIF2A; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000030673}.
FT DOMAIN 332..526
FT /note="Translation initiation factor beta propellor-like"
FT /evidence="ECO:0000259|Pfam:PF08662"
FT REGION 869..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1399..1440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1828..1854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1869..1890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..886
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..966
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..990
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 997..1045
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1419..1440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2352 AA; 274665 MW; F408EB25B6F6952E CRC64;
MSELLIRSKS GVKLYEFKKL ENLYESNIIF EYDGCIHDAI WSYDGNSFLL LHSIEGLLLI
SNYEEKKKRK IEKIACIGKY KELFDDENIK LIKHVQWSPN NRFIVFFFSY EEEKHNRLGN
LLVWNVKDKN ILCSFKIKKK SCSNWPVINF TNDDNYFFLQ KKTDIYIYDT LKLIQDHDNI
TYLHNNDIPL NYIYTWNQPN VLAIYMSSYM SDDKCRFFIV HTKNNFLGDV YIFKIKGLNN
SKIVSYNVRE DKEKADEMNV DGKNVNVKNV DGKNVDGKNV DENVDEKYVN VKNVDGKNVN
DVGGEINVDN NVSYKNDPSC VEKIKIELLI RKSFDNLDTL TCLWSISGQY LIFLVNTNDT
TNKSYGYLSN CYFCSLVSKN IHIKRINEQV AQDVKWSNIR DEFLIIEGKS DNIILLYDHD
LNVKCKIYSQ YKNTIKWGPF GNMIALGGFG NLAGDINFYY KEVDNSVSII KKYREACTVL
CDWSYDGTLF MTASTYPRMK VENVFKIYTY EGTLVNSYNF NELYDVKWKN VLPGFFKQPP
KPQPNLLDSS NKKSVYKIKN LDHLLNSTQN NTIINNNNNN NNNMNGINNN IPMNSINNNI
PMNSINNNIP MNSINNNIHM NSINNINVGM SYVNNMNNKM MNNNNNNNLT NPTSYSFDVY
DENNVNVNIN EVLEKDKTKT NKGMAGTTST SLSNLTSNLL NGHRKKKTEK VKNAYDWDVD
WRKKKSMGIM NSVMNTNNVM NMNNMMNMNN VMNTNNMMNM NNVMNTNNMM NMNNVMNMNN
IINTNNIINT NNIINTNNID MNQRDDYIPN EQTTQDDKNQ TLKNDKILNS NLNSSNKNIN
VMLDNIKSRD NSENGIIILQ NKLNNYHDKA NINDNMNKDE HVEEKKKQKK KKKKKEKKEE
KEKKEDHEKG KDKDKKEDHE KGKDKDKKED HEKGKDKEKD KDKDINNEQY NTSEQPIQIN
NNHMNDVNIN DDDKLYSNSK HTKEQSKLQE MGHIKTISLD DINKNKGKDN QTNEIKKDIK
DKEKNTEMVD SNMNDEKDQD KKKKKENKNK KSKKKKNDNN NVDGVYNDNV PKDKTYNDNN
NNNNNNNNKE VEKNNSSAGS NSFSNILLKI IKYKNDTNNT NNTNITNITN NTNNTYNTNN
TNDTYDNDQC HINKKNMNVE LNKDLDYVKR QINVPNSKHI MNSTNNNGTG VEHMSDMSTL
NCNKKNNDMS IRISNQYNNE NIKMYTNKNI PLHGDEFLKD IKNGKYNMSD MNITKDMMIN
NMKNNMILNH VLKNNDMKNN TIGEDNNNNM FNTSNINDIQ SINTLNNLIL ENALLRNELP
IYQSKGKDNE NATSRNNTND NMNSINSMNN VHNNVASNEN LINIFKKMLP HAKVNIVGNN
RNSTKSLDSY NMYDTQNNSS LNRETHQSFK RHDSFNHPYK EGNNNNNNNN NNNNNNNNKN
MFNEYAKEHL IKEMILKKYL MNNKEYDTIN NFSLNKIDDI QSIQSKVQIN NKSNVDGVNN
NNVDNVDYMN NQQYNMPQNL KNQLDNLDFF ELLKCYHSLN IQQIQIKLYW IYYKIQMFEQ
SNLLSCDNKD KKILYKLKEI RHILEYTNHL LKDHFIKNKE KYQSLLQQFI IILKHHDNLY
LQKREKLITD HYDKQNVVHF ICNIEKFIEK NMNLTDNFIS SNLNFIPSKT INNKLGRTNS
VIYENKNNIK NNDHHTRGSQ KITDNYNNID INKINHNKYV QNKYNDHNVS NNYIYHQNDA
NNNMNHLNQN LEFQKKFILH KMNDYFKNIN ATNEQKNIFL NKMNLTEEQK MFFLKQLNIK
DEEFIEPNNT KQPFVNCLNN NNNKIKNIDE KEKKDKTNKT NKTNQTNQTN QTNQTNQTNF
INHMNQTNQT NQTNQTNQTN QTNKKGGDTY IDSAYSRSSY FCINDPNADK NKENIKQNNE
KTDHNEDAIG GSPLLNLINK SHGQRVENNI NSMMNNLNHI NLMNNMNYFN NRADDNQGVE
NEQSKWLSQK NVLLNILKNQ KKLKDDNNVV VPNLNEENYM KNIKNELNKD INTFQFNNIP
ENISEKLKNI IHMNNKDGKD LQNHQADLIN YIYQNKQMDG VIHSYTNCND INEQAKMNLN
QTKDKLKNIS NLSTHSGKLE EQNNTHLQHL YSQQQRNLRN LMNTNEGDTN IPNVTQNKNH
INSNTSFLNT GNDENNNRNV NEFIRIMNNE CMSNLQKKNV NNNNPLNNNN NNSNNNKTLV
GMKNIVEEKK QTIINNDTNI ISNHFLTNEH QGKGDTTKTF YINKKNQNVL SQSLNNQTGV
VNKGISNKHK TNNIVSNKSL NNSLDKKNVQ QSNMLDLEDT KRPDALRDKC WQYVDPKGVV
QVRTKKKKKN IK
//
