ID   W7JML7_PLAFO            Unreviewed;       194 AA.
AC   W7JML7;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=Vacuolar protein sorting-associated protein 29 {ECO:0000256|ARBA:ARBA00017767, ECO:0000256|RuleBase:RU362040};
GN   ORFNames=CK202_0521 {ECO:0000313|EMBL:PKC49787.1}, CYL21_2815
GN   {ECO:0000313|EMBL:KAF4329621.1}, PFNF54_04894
GN   {ECO:0000313|EMBL:EWC86163.1};
OS   Plasmodium falciparum (isolate NF54).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC86163.1, ECO:0000313|Proteomes:UP000030673};
RN   [1] {ECO:0000313|EMBL:EWC86163.1, ECO:0000313|Proteomes:UP000030673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF54 {ECO:0000313|EMBL:EWC86163.1,
RC   ECO:0000313|Proteomes:UP000030673};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Plasmodium falciparum NF54.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PKC49787.1, ECO:0000313|Proteomes:UP000232684}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF54 {ECO:0000313|EMBL:PKC49787.1};
RA   Bryant J.M., Baumgarten S., Scheidig-Benatar C., Scherf A.;
RT   "Plasmodium falciparum NF54 genome assembly.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:KAF4329621.1, ECO:0000313|Proteomes:UP000754359}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF54 {ECO:0000313|EMBL:KAF4329621.1};
RA   Baumgarten S., Treeck M., Scherf A.;
RT   "Genome assembly of Plasmodium falciparum NF54 DiCre.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VPS29 family.
CC       {ECO:0000256|ARBA:ARBA00005945, ECO:0000256|RuleBase:RU362040}.
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DR   EMBL; KE123877; EWC86163.1; -; Genomic_DNA.
DR   EMBL; QFXU01000012; KAF4329621.1; -; Genomic_DNA.
DR   EMBL; NYMT01000001; PKC49787.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7JML7; -.
DR   SMR; W7JML7; -.
DR   EnsemblProtists; EWC86163; EWC86163; PFNF54_04894.
DR   VEuPathDB; PlasmoDB:PfNF54_140011700; -.
DR   OMA; VRGNMDY; -.
DR   Proteomes; UP000030673; Unassembled WGS sequence.
DR   Proteomes; UP000232684; Unassembled WGS sequence.
DR   Proteomes; UP000754359; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0030904; C:retromer complex; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR   CDD; cd07394; MPP_Vps29; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR024654; Calcineurin-like_PHP_lpxH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR000979; Phosphodiesterase_MJ0936/Vps29.
DR   InterPro; IPR028661; Vps29.
DR   NCBIfam; TIGR00040; yfcE; 1.
DR   PANTHER; PTHR11124:SF12; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29; 1.
DR   PANTHER; PTHR11124; VACUOLAR SORTING PROTEIN VPS29; 1.
DR   Pfam; PF12850; Metallophos_2; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030673};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          12..149
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF12850"
SQ   SEQUENCE   194 AA;  21774 MW;  3F87221E6DD8B644 CRC64;
     MSGKLEDIGE LVLLIGDFHS PIRNLGLPDC FKELLKTDKI KHVLCTGNVG CNENLELLKN
     IADSVHITKG DMDDNFDFPE DITLCIGDFK ISLIHGHQII PWGDMNALLQ WQKKYDSDII
     ISGHTHKNSI VQYEGKYFIN PGSVTGAFQP WLSEPTPTFI LMAVAKSNIV LYVYEEKNGK
     TNVEMSELHK STVI
//