ID W7JXH8_PLAFO Unreviewed; 909 AA.
AC W7JXH8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Translation elongation factor G {ECO:0000313|EMBL:EWC89738.1};
GN ORFNames=PFNF54_01317 {ECO:0000313|EMBL:EWC89738.1};
OS Plasmodium falciparum (isolate NF54).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5843 {ECO:0000313|EMBL:EWC89738.1, ECO:0000313|Proteomes:UP000030673};
RN [1] {ECO:0000313|EMBL:EWC89738.1, ECO:0000313|Proteomes:UP000030673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF54 {ECO:0000313|EMBL:EWC89738.1,
RC ECO:0000313|Proteomes:UP000030673};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum NF54.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE123764; EWC89738.1; -; Genomic_DNA.
DR AlphaFoldDB; W7JXH8; -.
DR EnsemblProtists; EWC89738; EWC89738; PFNF54_01317.
DR OMA; MDDMVGG; -.
DR Proteomes; UP000030673; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01886; EF-G; 1.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR CDD; cd04088; EFG_mtEFG_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 2.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EWC89738.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000030673}.
FT DOMAIN 71..350
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 406..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 104972 MW; 006646B18DF8B2FF CRC64;
MRYIILYMWN KNNNVYLSNG KVKREKRNGR GKLYILNRYV RNDIIKPHKN IIKNIFRLKL
VNGSTKNVEL ENYRNIGIIA HIDAGKTTTT ERILYYTNVI KKIGEVHEGL STMDYLDIER
EKGITINAAV TTCYWNGSEK NLEDYRINII DTPGHVDFTA EVEKSLRVLD GGVVVFDSSE
GVESQSETVW KQANQYNISR IIFLNKLDKV GANFEGCIEE IKRKLNKKIL ILYVPVFEMS
KFISTIDILK EKMIVYKNAH DFIFEDIPKE HYNLFLKYKN LLFEQIAENF NSFLDNYLND
KAMNIQEIEY YIRKLVVEEK YNVVMCGSAL KNKNVQMLLD MVVKYLPSPI DSIKNYKKQI
IYIHDVNRRG EKIVPANSES NLKKEKVMLK KNINKGEEHN VENKIPAHEI NKDSMNIKKG
TTESDTSSST CVADSNNISG PNNISSERSQ NNMKDDQINY QDSISDELNE SNIKNYKRKM
VGLIYKIMND QHLGNINYVR IYEGQINRGE FIYNNRTKKS EKISKIFFIH SSEKYELENA
KAGDIVGLVG LKDTQIGDTL SNVFLRAELK RIKDIPPIIS YYIYNKNKNE YEKLINALIK
IKKEDHSFFY HINQDTKDLL ISGVGELHLQ IIINKIEKDF NIPIIYGKPQ ISYKETFVES
VKARGKYIKQ SGGRGQYGDV HIEIEPMYNY NEQEDEEGEQ TDQEQNGVDE KEKKEQKYIE
QDIDNNSMNI NTSEVNNNII IKNEITCGAI PSVYFDAIYT GIREQCNMGI LFNSPVINIV
VRIVDGSFHP VDSNEHAFKL AAGLAIKEAA KKTSIRLLEP IMNLNVTVPT EYLGDVISDL
VKKRGKIQHI DESDEFTKEI TARAPMASVL SYVSDLRKIT KGRGNYTMTL HKYSLVPEYI
QEQILQKKE
//
