ID   W7LSD1_GIBM7            Unreviewed;       532 AA.
AC   W7LSD1;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Cytochrome P450 oxidoreductase {ECO:0000313|EMBL:EWG38390.1};
GN   ORFNames=FVEG_01613 {ECO:0000313|EMBL:EWG38390.1};
OS   Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS   fungus) (Fusarium verticillioides).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG38390.1, ECO:0000313|Proteomes:UP000009096};
RN   [1] {ECO:0000313|EMBL:EWG38390.1, ECO:0000313|Proteomes:UP000009096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA   Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA   Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA   Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA   Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; DS022243; EWG38390.1; -; Genomic_DNA.
DR   RefSeq; XP_018744581.1; XM_018888616.1.
DR   AlphaFoldDB; W7LSD1; -.
DR   GeneID; 30059890; -.
DR   KEGG; fvr:FVEG_01613; -.
DR   VEuPathDB; FungiDB:FVEG_01613; -.
DR   eggNOG; KOG0158; Eukaryota.
DR   OrthoDB; 3184603at2759; -.
DR   Proteomes; UP000009096; Chromosome 6.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd11062; CYP58-like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR   PANTHER; PTHR24305:SF147; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW   Iron {ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009096}.
SQ   SEQUENCE   532 AA;  59891 MW;  8F68AF966228840F CRC64;
     MADASWSVIH GALTSLTAQD WTVAFISCWF VFKVLQALYN VSPLHPLSKI PGPKLAAATY
     LPEFYYDVIL VGRYTHAIKQ MHEKYGPIVR INPNELHCAD MSFSDEIYAV GGRKRDKPFH
     QVNGSAAGTG NAFGTPDHDI HRARRAPVAK FFSRAMIARL EQEVHDLAQK LCNKLLAENK
     DEKDRKPFEI AHAYSCFTSD AISSYCFGEA FGLLSRSQWQ PNYREATLAV LKPVFFFRFF
     PILVSSVKLG KYFVNILPTD IALLIRTLQI DIPSRVQKTK NELDAGIVYD RPTIFADLLQ
     SELHDSEKKQ DRLVEEAVTI VNAGTETTSW ALAVITYFLL SQPETLAKLQ DELKQVVDDP
     CHLPSWTTLE QLPYLGAVIN EGLRLSYGVS SRTARVPTAE DLVYRGEFNK KPTTLVLPRG
     YAIGMSAAIA HHDESVFPDS YTFAPERWID EDNKIRKDLE KSMIAFSKGS RGCLGKNLAL
     CELYLSLAAL VLRVMPCMRL YETTEKDVRY DHDMFVPMTE SGSKGVRVII ES
//