ID W7LZR0_GIBM7 Unreviewed; 708 AA.
AC W7LZR0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Nitrogen permease regulator 3 {ECO:0000256|ARBA:ARBA00017880, ECO:0000256|RuleBase:RU368069};
DE AltName: Full=Required for meiotic nuclear division protein 11 {ECO:0000256|ARBA:ARBA00030028, ECO:0000256|RuleBase:RU368069};
GN ORFNames=FVEG_01437 {ECO:0000313|EMBL:EWG38112.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG38112.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG38112.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC amino acid starvation. Required for meiotic nuclear division.
CC {ECO:0000256|ARBA:ARBA00025376, ECO:0000256|RuleBase:RU368069}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000256|RuleBase:RU368069};
CC Peripheral membrane protein {ECO:0000256|RuleBase:RU368069}.
CC -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000256|ARBA:ARBA00010546,
CC ECO:0000256|RuleBase:RU368069}.
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DR EMBL; DS022242; EWG38112.1; -; Genomic_DNA.
DR RefSeq; XP_018744303.1; XM_018888400.1.
DR AlphaFoldDB; W7LZR0; -.
DR STRING; 334819.W7LZR0; -.
DR GeneID; 30059734; -.
DR KEGG; fvr:FVEG_01437; -.
DR VEuPathDB; FungiDB:FVEG_01437; -.
DR eggNOG; KOG3830; Eukaryota.
DR OrthoDB; 1381214at2759; -.
DR Proteomes; UP000009096; Chromosome 1.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-UniRule.
DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR InterPro; IPR005365; Npr3.
DR PANTHER; PTHR13153; CGTHBA PROTEIN -14 GENE PROTEIN; 1.
DR PANTHER; PTHR13153:SF5; GATOR COMPLEX PROTEIN NPRL3; 1.
DR Pfam; PF03666; NPR3; 1.
PE 3: Inferred from homology;
KW Meiosis {ECO:0000256|RuleBase:RU368069};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW Signal {ECO:0000256|RuleBase:RU368069}.
FT REGION 66..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..605
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 79739 MW; D9CDA5E4CA676467 CRC64;
MAVPSVTSDN FLAVALVVNR SRDGPAFVFH YPANIEPHSK PSSSAGADLE DILLERLSQQ
SFSDVADDVP LPKQGRNADE HSFTESGSQI VPWERVAGFP ARDLAGILTP ARPYHKKLFQ
LSLDPLYCVS YPIHVPENGR WKKPKKASRA DKRSAYNEEQ PAPHEVDPLP SGKAPEQPVE
EKDGKKEDGK DKDDEKRSSM TMFNLVFILN PSSNEVKDVV ESMYDHIIKK VSKAFKYSQQ
HSEFVWKESK RILVAKDKAR EERKRMSVLW KEILQSSSLA ATMHDIYEAV SQNKIAALHL
DTAAGSLTPS VQIPIPFYID DLPQGEEGTQ RGLWLTTANT FISQDALEEP GFLDRNFALL
LTDDEKKIIA ELQADPDPTT ASMVEFVRLS KPTQSFYQVG QSNILTLGQV RKYAQHFIFW
RRAIAIPPLH AKDQYILSPN SDLSRLPLDT LEWQRAFPLA PPLPNFLAEL SQAPRPYKQF
SPSKAHRPTY LLMLSWLMRR GWVTQLCTFA YVVVWPEIMY EVEYEIEAEE LRAAADADAY
KSKEKEAKDD ASTSASVPRT SESSEGHSGT DGSHVPTVAE QAAEKARLER IASKAQRDAA
EKATAHARKP VPVATAHPSV NDHPHLQGLT PHIILDAKKA TGKESRYLSA IARRFNDEKL
ANSWQVMCKY FDGRCALERI ALQEDMKRKL VWNTLTAMSE YLLCTRHW
//
