ID W7M710_GIBM7 Unreviewed; 1171 AA.
AC W7M710;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN ORFNames=FVEG_04861 {ECO:0000313|EMBL:EWG43350.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG43350.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG43350.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS022246; EWG43350.1; -; Genomic_DNA.
DR RefSeq; XP_018749541.1; XM_018892775.1.
DR AlphaFoldDB; W7M710; -.
DR STRING; 334819.W7M710; -.
DR EnsemblFungi; FVEG_04861T0; FVEG_04861T0; FVEG_04861.
DR GeneID; 30062894; -.
DR KEGG; fvr:FVEG_04861; -.
DR VEuPathDB; FungiDB:FVEG_04861; -.
DR eggNOG; KOG3548; Eukaryota.
DR HOGENOM; CLU_008949_0_0_1; -.
DR OMA; PCLAPQW; -.
DR OrthoDB; 1406366at2759; -.
DR Proteomes; UP000009096; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd17745; BRCT_p53bp1_rpt1; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR047249; BRCT_p53bp1-like_rpt1.
DR InterPro; IPR047252; TP53BP1-like.
DR PANTHER; PTHR15321:SF3; TP53-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15321; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT DOMAIN 889..1012
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 33..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 224..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..627
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..738
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1171 AA; 127732 MW; B543666C33726F05 CRC64;
MTDSQMLAQA GSNETQDSQP IFEAYRAEFG VGTLSSSPPK YVPSSKITTT SPKQIPSPTS
EVVVPSSDPP VIDLAVPATT VHHGALSDKA RPGGPTTEND DPSHWDTTRV ALTHSKKQCA
TLEADVVNGV AQGLQDRVNS NSNVNLSVRV PATFIKPKHL ANSSARHDSP QPQSVQDNAP
KPLIKCLKPS ASAVTAALRK MDYSQQTPTQ VNDDRDYSEY CDIVPSSPVN GDTQPASHEP
RTLQDDDTGA VNFANMSELG RPSSQISEDA GFDNTRGDWR HPDGTSQLNN GQTPHRPHAP
TFETPAVPNN PFAARPSIAA PLAGSQLFGQ TQFSSAIKHI SPTSSRPSPK LFNSISPNLI
ETSPLKNRAN VSSPSDIRTS SPQRRLHDIP ETSLQDLDGG PIRAVTPVND QSTAGEMIPE
SPPSTDPTTR AKAPRSSNTT EPMAHYEPMK KSQERKSMEN FVIPPWASDD DSDDAIRRLE
RRKKIERKKA QAAEEMGRVS FTPKIRRNSA EQPSRKKRKV LPLEEPEINL NPSPKTDRGK
GQELPPLVDD SQKGLVVSNE TLPVTSTKAT PGNSAPDNPQ IDHDGDIVLV DADKVVVDDD
MIPATSPAPS LPPTAPVEQP PPSEPELPQL RVEDEGLPQG PTDHSEPSSL PPARKRTTRT
YGRAARQKRR NPFLSSSFSD GLMSDLNPKP MPISSPLQKV TAVSMIEEEP EEELPLSRTA
EDKSEKKSAS RSRKPARDVY ADLPPPMTTR SRRSDRADTA PVTPLASRSV GQVPPTSSSL
SILSTTPLPS DKTTPGTQDS PGSGRPESVT LPSPRDSRDC YKEEAGKGSK TGSPQPAKRA
ARVSKRFSYL DSDSTDELHL SPAASVLERS MVHSKSSRSF KQSFAQAHRA GRLFERMVFA
ISFSDQFKAQ ERKKLATKIT QSGGIILAEG FQDMFEHSSI MDATHPVIDE QDSLQLTKHI
SESGFTALIA DKHSRKVKYM QALALGLPCL APQWIMTCFN KGVIVDWEPY VLCAGESAVL
GNAIRSRILV PYSATEAKLA EVIQQRPRLL DGQRVLVVID SKKSRNEAKE PYIFLATLLG
PSISRVFSTQ QARELLLEHQ KAGTPFDWLY LDKGTGTVDA VLAPTETTGN KKRRRSTATQ
PRIENIRVLS DELVIQSLIL GRMVEEEEMY T
//
