ID W7MF82_GIBM7 Unreviewed; 693 AA.
AC W7MF82;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:EWG49606.1};
GN ORFNames=FVEG_09091 {ECO:0000313|EMBL:EWG49606.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG49606.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG49606.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004137}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004137}; Intermembrane side
CC {ECO:0000256|ARBA:ARBA00004137}.
CC -!- SIMILARITY: Belongs to the NADH dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00005272}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS022253; EWG49606.1; -; Genomic_DNA.
DR RefSeq; XP_018755797.1; XM_018898007.1.
DR AlphaFoldDB; W7MF82; -.
DR STRING; 334819.W7MF82; -.
DR GeneID; 30066774; -.
DR KEGG; fvr:FVEG_09091; -.
DR VEuPathDB; FungiDB:FVEG_09091; -.
DR eggNOG; KOG2495; Eukaryota.
DR OrthoDB; 48029at2759; -.
DR Proteomes; UP000009096; Chromosome 5.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0003954; F:NADH dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006116; P:NADH oxidation; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 3.50.50.100; -; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR045024; NDH-2.
DR PANTHER; PTHR43706; NADH DEHYDROGENASE; 1.
DR PANTHER; PTHR43706:SF50; NADH DEHYDROGENASE (UBIQUINONE)-RELATED; 1.
DR Pfam; PF00036; EF-hand_1; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 539..574
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 693 AA; 77499 MW; E67E9E1D6C7115EC CRC64;
MPVSSMMAAR LARAGQNRAI TSSRGFKPSL GPRPLYSSQS RSFVKLTGAS PTITKGSPAT
SRTTRQLPSQ FFVRALSGKP LPQGKSKVVN FCYRLAAWVG ISISVIGVGI VGFFIYDAST
YFEHPTQSDI DVSKIALQPR SGGEKNLPIA EVFIDDDDSE EKRRLKDKPR LVILGGGWGG
VALLKELNPD DYHVTVISPT NYFLFTPMLP SATVGTLELR SLVEPIRRIL SRVNGHFIRA
KAEDIDFSHK MVEVSQVDAN GKDIKFYVPY DKLVVAVGST TNPHGVKGLE NAYFLKDIND
ARMIRNQVIQ NFELANLPTC PDEERKRLLS FCVSGGGPTG VEFAAELFDL LNEDLTRHFP
RLLRNEISVH LIQSRGHILN TYDETVSRYA EERFARDQVD VLTNSRVKEV LPDKIIFTQK
QEDGTMITKE LPIGFCLWST GVSQTQFCQT LAAKLGKSQT NRHALETDTH LRLNGSPLGD
VYAIGDCSTV QNNVADHVVT FLRSLAWKRG KDPETLQLSF ADWRGVAEDV KRRFPQSINH
LKRVDKLFKE FDKDKSGTLD FDELTQLLKQ VDDKLTSLPA TAQRAHQQGQ YLARKFNKMA
RMHEGLNAND IREGDVDAAV YKAFEYKHLG SLAYVGNSAI FDLGEGRSLA GGLWAVYAWR
SVYFAQSVSL RTRLLMAMDW TKRGLFGRDL MSF
//
