ID W7MRL2_GIBM7 Unreviewed; 508 AA.
AC W7MRL2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Protein SSH4 {ECO:0000256|ARBA:ARBA00017626};
DE AltName: Full=Protein ssh4 {ECO:0000256|ARBA:ARBA00016528};
GN ORFNames=FVEG_07407 {ECO:0000313|EMBL:EWG47247.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG47247.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG47247.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7600 {ECO:0000313|EMBL:EWG47247.1}, and M3125 / FGSC 7600
RC {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [2] {ECO:0000313|EMBL:EWG47247.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=7600 {ECO:0000313|EMBL:EWG47247.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Components of the endosome-vacuole trafficking pathway that
CC regulates nutrient transport. May be involved in processes which
CC determine whether plasma membrane proteins are degraded or routed to
CC the plasma membrane. {ECO:0000256|ARBA:ARBA00025244}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004639}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004639}. Vacuole membrane
CC {ECO:0000256|ARBA:ARBA00004576}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004576}.
CC -!- SIMILARITY: Belongs to the SSH4 family.
CC {ECO:0000256|ARBA:ARBA00006990}.
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DR EMBL; DS022250; EWG47246.1; -; Genomic_DNA.
DR EMBL; DS022250; EWG47247.1; -; Genomic_DNA.
DR RefSeq; XP_018753437.1; XM_018896053.1.
DR RefSeq; XP_018753438.1; XM_018896054.1.
DR AlphaFoldDB; W7MRL2; -.
DR STRING; 334819.W7MRL2; -.
DR EnsemblFungi; FVEG_07407T0; FVEG_07407T0; FVEG_07407.
DR GeneID; 30065210; -.
DR KEGG; fvr:FVEG_07407; -.
DR VEuPathDB; FungiDB:FVEG_07407; -.
DR eggNOG; KOG1477; Eukaryota.
DR HOGENOM; CLU_016552_1_1_1; -.
DR OMA; FFFKYTR; -.
DR OrthoDB; 5479594at2759; -.
DR Proteomes; UP000009096; Chromosome 8.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR CDD; cd12910; SPRY_SSH4_like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035780; SPRY_Ssh4-like.
DR PANTHER; PTHR12864; RAN BINDING PROTEIN 9-RELATED; 1.
DR PANTHER; PTHR12864:SF54; SPRY DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 81..277
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 314..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..443
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 55440 MW; B8B91599CA134709 CRC64;
MGLSSNPSSA FTGVVIGLVS SFGSIVLIAL VIFIFWVSGC ASTGRIILDR LGRPGEYDDE
QAFARDEAEA LEVMDDMSRQ EYLRAKAWVT ANPPESMQTD ISLSQYLAIQ EKGVSAWEFE
PELEIANCFV EARTEIEFFD SECTVMSNLP VPKQNDVYYW EAKIYEKPEN TLLSIGMATK
PYPLFRLPGY HKYSVGYQST GARRYNQPFG ATPYGPPLVQ GDVVGVGYRP RTGAIFFTRN
GKKLEEVVHG LKAQNFFPAI GANGPATIHV NLGQAGFVFI EANVKKWGLA PVTGSLAPPP
PYGSEQGSIL LEAGTKDGNT YPQGRQHSHS ITASSYNTRN PSNDLNPSHG RTRSGNFRVL
PPTSPGPVRS STDISLAHFV PNEENGEASS NVVPQQETHD HNPLHLHLED ATNPPPEYQS
PDHSGSEDGR YGSDSEEDTP LIRVMNRSRG NSSATVLPSR QTPSPRQPPV PSYSDAMREG
AGRDRSDSAR SPPPNRTPSN RPRSSTSA
//
