ID W7MXN6_GIBM7 Unreviewed; 794 AA.
AC W7MXN6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=XPG-I domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FVEG_11277 {ECO:0000313|EMBL:EWG52550.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG52550.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG52550.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022257; EWG52550.1; -; Genomic_DNA.
DR RefSeq; XP_018758741.1; XM_018900463.1.
DR AlphaFoldDB; W7MXN6; -.
DR STRING; 334819.W7MXN6; -.
DR GeneID; 30068800; -.
DR KEGG; fvr:FVEG_11277; -.
DR VEuPathDB; FungiDB:FVEG_11277; -.
DR OrthoDB; 1779469at2759; -.
DR Proteomes; UP000009096; Chromosome 9.
DR GO; GO:0008821; F:crossover junction DNA endonuclease activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR CDD; cd09906; H3TH_YEN1; 1.
DR CDD; cd09870; PIN_YEN1; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR041177; GEN1_C.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR InterPro; IPR037316; Yen1_H3TH.
DR PANTHER; PTHR11081:SF71; ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED; 1.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR Pfam; PF18380; GEN1_C; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096}.
FT DOMAIN 1..101
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 108..179
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 456..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..595
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..680
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 87207 MW; CFD998C459EA6F3E CRC64;
MGIKGIYQEV GEGERVALLK LAAESLEKQG RPLRIAIDIA IWQFQNQAAQ GGTNPEIRTL
FYRLVRLLAC PVEPIFVFDG PYKPAVKRNK KSGRGDSFAN AQAKRLIRLF GCNTHDAPGE
AEAECALLQK HGVVDMVLTE DVDALMFGCT KMLRQWSPAS KRDTTPTHVS LFDTEKMRLD
QQGLDREGMV LVALMSGGDY DPNGLPGCGI KVAVEAAKAG FGRDLCRLKA VDKEGTAAWR
NSLIHELRTN ESGHFKRKNK ALAIPETFPD FKVLRSYTHP VVSPGESIDE IREKVHLKRE
IQFEDLREFT REVFGWDYRV GALKFIKVLS HAVLVQKLQA LEGHDNADYV KGIAGFRSDL
KNDLVAQVRI QHIPSEIVPI DLSKEEDEKI MQARGGLALN SDDEIDDAEN IEESTAKRQP
APFNPSGRQG VWVLEILAKS RIPEVFADAQ VVQKAADKKK QQAKGPKTKG IRSKPGPKTG
MPAGALNKFV RASKPHTVST VTSKAVPKEN EIIASSIRPT TSRRLRIPSP LEPSKQSAST
SGSTVRQTTT PWTLASSQVT PRTRKPANEQ QAIVITSSPP CAADSPPPSP SPRPRTRVPA
SRDLPDPMCA IPMSSGSPQR LKNSALNARR VNPPASSQTS QPPKMKQMSM DMFTKKAKNT
SSSQTSISKS SLPASKKHQP RSQTSFDDDF DSDSSTDLAP LSSLISRSSA SPNKRQQSSL
PPDRNATPSP APARKKKLLI PKASAMGFYE EVEVDAEERD ELMARETAAL ERRGVKAKIF
RTSDVGFIDL TQDD
//
