ID W7N0F7_GIBM7 Unreviewed; 832 AA.
AC W7N0F7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Alpha-type protein kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FVEG_12010 {ECO:0000313|EMBL:EWG53615.1};
OS Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS fungus) (Fusarium verticillioides).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=334819 {ECO:0000313|EMBL:EWG53615.1, ECO:0000313|Proteomes:UP000009096};
RN [1] {ECO:0000313|EMBL:EWG53615.1, ECO:0000313|Proteomes:UP000009096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M3125 / FGSC 7600 {ECO:0000313|Proteomes:UP000009096};
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., Xu J.R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.H., Li L., Manners J.M., Miranda-Saavedra D., Mukherjee M.,
RA Park G., Park J., Park S.Y., Proctor R.H., Regev A., Ruiz-Roldan M.C.,
RA Sain D., Sakthikumar S., Sykes S., Schwartz D.C., Turgeon B.G.,
RA Wapinski I., Yoder O., Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A.,
RA Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
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DR EMBL; DS022259; EWG53615.1; -; Genomic_DNA.
DR RefSeq; XP_018759806.1; XM_018901339.1.
DR AlphaFoldDB; W7N0F7; -.
DR EnsemblFungi; FVEG_12010T0; FVEG_12010T0; FVEG_12010.
DR GeneID; 30069489; -.
DR KEGG; fvr:FVEG_12010; -.
DR VEuPathDB; FungiDB:FVEG_12010; -.
DR eggNOG; ENOG502QVA3; Eukaryota.
DR HOGENOM; CLU_011332_0_0_1; -.
DR OMA; AHDDNIK; -.
DR OrthoDB; 2968804at2759; -.
DR Proteomes; UP000009096; Chromosome 4.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd04515; Alpha_kinase; 1.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.20.200.10; MHCK/EF2 kinase; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR004166; a-kinase_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR47763; ALPHA-PROTEIN KINASE VWKA; 1.
DR PANTHER; PTHR47763:SF1; ALPHA-PROTEIN KINASE VWKA; 1.
DR Pfam; PF02816; Alpha_kinase; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00811; Alpha_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51158; ALPHA_KINASE; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000009096};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 164..244
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 483..701
FT /note="Alpha-type protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS51158"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..427
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 92395 MW; B7129637D34224D0 CRC64;
MSAPPPYSPP GSTGNDGETR DIRTLTDTSS ATSTASSAST ILPPYPPSRD RTVPIRSDEP
RSMPPIAGAL QRLRSPGDSG TSNATSSGTR ERLRQMEIER DDLRRAMQQE RAINDRLKRE
AGLTGLSAAE ARLRVLELKR EAQAAAQMKR TPNEGMFKAA CATDLLFLMD TTSSMGPFIA
AAKEQVKKIM EDITETFYNE AEVRIAVVSY KDHCDKNHIQ FIDFTTDVEK VRGFIDKLKA
RGGGDAPEDV LGGIQQAVNA SWKHQTRCII HIADAPPHGN IFHSWTEKSD DYYTPGSEPH
KLHYQPLLKQ MIGLNLNYAL LRILSATDKM AYVFLQEYAA ASADCKLLKT NPHYREALKA
NSGPRSSVLG SSKGTAKGGL LFEEAELGTT YSALRHLVVK SVTSSASRTA VRMSESSSRT
GEKGTKTAQM SHLDAIGEAE DDEFNEKGSE TILEDVDKKW SDQSWFEDKL VVEGFSPDTV
IHRSGTLNDM MAHDDNIKLS VMELNVHKRR MPFAQGALRL AYCAKTTHST NPYVVKSFKR
GGKRLAHLAE DMRCQALCKA FALEFNALTG DKHAIDFIVT SCLKGKSGDS GTDYISLEPF
IEGDYVKYNN NCSYVNEDNP DDEFNKAAQA FSHFTYERSW GSFLVCDLQG VGHVLTDPAI
HTLDPERFKL ADTNLGREGF KFFFATHVCN EICTQLELKS KASMISSEKA SFREWWPTID
STACCSNKLC GKIIQVTNAN KSEEFPGCNW CDACWPQLEA TKEKVICVAP GTHHEFDVSR
FYWESQGRVA PRKCEDHRER DETVARTSVM GGNFFGRLRG ATKKKSISGK AW
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