ID W7P4T6_9ENTR Unreviewed; 490 AA.
AC W7P4T6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Uric acid transporter UacT {ECO:0000313|EMBL:EWG76482.1};
GN Name=uacT {ECO:0000313|EMBL:EWG76482.1};
GN ORFNames=P349_01889 {ECO:0000313|EMBL:EWG76482.1};
OS Enterobacter sp. DC4.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Enterobacter.
OX NCBI_TaxID=1395580 {ECO:0000313|EMBL:EWG76482.1, ECO:0000313|Proteomes:UP000019283};
RN [1] {ECO:0000313|EMBL:EWG76482.1, ECO:0000313|Proteomes:UP000019283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DC4 {ECO:0000313|EMBL:EWG76482.1};
RX PubMed=24625871;
RA Gan H.M., Triassi A.J., Wheatley M.S., Savka M.A., Hudson A.O.;
RT "High-Quality Draft Whole-Genome Sequences of Three Strains of Enterobacter
RT Isolated from Jamaican Dioscorea cayenensis (Yellow Yam).";
RL Genome Announc. 2:e00170-14(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWG76482.1}.
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DR EMBL; AZUB01000002; EWG76482.1; -; Genomic_DNA.
DR RefSeq; WP_032647264.1; NZ_AZUB01000002.1.
DR AlphaFoldDB; W7P4T6; -.
DR PATRIC; fig|1395580.4.peg.1870; -.
DR Proteomes; UP000019283; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 36..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 490 AA; 51986 MW; C2C73A1F265C8981 CRC64;
MKDSAIPASR STASTAPVDE VLPVTQMILY GLQHVLVMYA GAVAVPLVVG NAVGLPAEHI
ILLISADLFI CGAATIVQSM GIRPWLGCRL PLIQGCTFAA LIPMVLIGKE YGIGAISGSV
IVSGIFILCC APWISRLIRF FPRVVMGSIV TLIGLSIMPV AGGWIGGGSS EMQGFGDLFS
LLMAAITLVI ILNLYTFATG VVKNTAVLIG LIIGTILWSF FKPLDFHLVN ATPWLHLPLV
MQFARPEFHI VPVALLSMVM VVVMVETMSS IMATGDIVGK KVDATMLRNG LNTCGLATTI
CGFFNLFPYA AFAQNVGLIG LTGVRSRFVV SVSGAILILM GLFSKMAALV VLIPKPILGG
AGIVMFGMVA VSGIRTLGQV DYRNNNNGMV VALTLGLGMM LVLVPNLFTQ FPPMMQLFLH
SGITIGTLTA IVANLTLNGS VPLRISHDIP EPDPLPPSAA ARNMAVRTVR MWLLLRKVQK
GQQPQHSGGE
//
