ID W7PZE6_9GAMM Unreviewed; 910 AA.
AC W7PZE6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Q427_11275 {ECO:0000313|EMBL:EWH01960.1};
OS Halomonas sp. BC04.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1403540 {ECO:0000313|EMBL:EWH01960.1, ECO:0000313|Proteomes:UP000019279};
RN [1] {ECO:0000313|EMBL:EWH01960.1, ECO:0000313|Proteomes:UP000019279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC04 {ECO:0000313|EMBL:EWH01960.1,
RC ECO:0000313|Proteomes:UP000019279};
RA Farooqui S., Greene A.C., Patel B.K.;
RT "Draft Genome Sequence of Halomonas Strain BC04, an Aromatic-degrading
RT moderate Halophilic Bacterium.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH01960.1}.
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DR EMBL; AZQX01000132; EWH01960.1; -; Genomic_DNA.
DR AlphaFoldDB; W7PZE6; -.
DR PATRIC; fig|1403540.3.peg.2111; -.
DR Proteomes; UP000019279; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019279};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..78
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 86..157
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 158..212
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 209..279
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 280..334
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 366..499
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 508..762
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT DOMAIN 777..892
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
SQ SEQUENCE 910 AA; 101404 MW; 1E9712F00556F1F4 CRC64;
MLSLAMAVFS ILTAVGIFTF AVWSIRRRIL HPLLRLETSV NHVTEDLKQP LPAFSDDEIG
NLAQAFESLR ASLVEDIERR EAAETELRKL SHAVEQSADS VIITNRHREI EYVNKAFEQL
RGYQRDDIIG MNARIFKSQE RNSPTLYQSL RDALEKGDTF RATLLNLDAS GETYYEEIAI
SPLLDPSGEI THYVANSRDV TERIHAEQEL QKLNQAIDQS VSSIVITDAN GITEYVNPQF
TRTTGYAPEE IKGRRIPLLE PGRLPRSQYR NLLRTLQQGK VWEGEVLSRR KDGESYWELT
SISPVRNRHG IITHFVGIQY DISERKQMEE QINQLAFYDS LTNLPNRALL AQRFDKVASQ
ALQRGKQVAL LSLDISRFHL LNDSLGHRVG DKVLQAVGQR LAVCARQQDM VTRYAGDEFV
VILSDAPDSQ GIAAVAQRMI DTVSRPLTIE CHDLRISMHA GISVLPRDGQ DLEALLGNAT
TAQHLAAREG KNTYRFFTED LNAAAQQRLA LEQDLRRALE DNALELHYQP KVDLATGEVV
GMEALARWHH PSEGHISPMT FIPIAEDTGL IQPLGEWALR QACLQGQAWR HQGLGRLNMA
VNLSTRQLQQ VDLAASVGRI LADTGFPPEL LELELTESAV MERPEETIRV LNELKALGVQ
LAVDDFGTGY SSLAYLRRFP FDTLKIDRSF ITNITTSPDE ASIAQTIIAM GRGLRLQVVA
EGVETQAQAA TLRRHHCDQL QGYLFSRPLP ARELETLLRE RRRMTLPDSN SAADDRSLLL
MDTDADAIAA LCPPLQEAGY RPLATTHIDE AFDLLALNGI RVVVGGLHLP EMPGLEFFKH
IRALYPDVAC LALAAPEDTA RVTEFVESGL LQGWLASDCQ GEALLARVQE AFSLTALPAA
SQDAALDTSP
//
