ID W7QJB9_9ALTE Unreviewed; 885 AA.
AC W7QJB9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:EWH11981.1};
GN ORFNames=DS2_02318 {ECO:0000313|EMBL:EWH11981.1};
OS Catenovulum agarivorans DS-2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Catenovulum.
OX NCBI_TaxID=1328313 {ECO:0000313|EMBL:EWH11981.1, ECO:0000313|Proteomes:UP000019276};
RN [1] {ECO:0000313|EMBL:EWH11981.1, ECO:0000313|Proteomes:UP000019276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-2 {ECO:0000313|EMBL:EWH11981.1,
RC ECO:0000313|Proteomes:UP000019276};
RX PubMed=24604650;
RA Shan D., Li X., Gu Z., Wei G., Gao Z., Shao Z.;
RT "Draft Genome Sequence of the Agar-Degrading Bacterium Catenovulum sp.
RT Strain DS-2, Isolated from Intestines of Haliotis diversicolor.";
RL Genome Announc. 2:e00144-14(2014).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH11981.1}.
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DR EMBL; ARZY01000002; EWH11981.1; -; Genomic_DNA.
DR RefSeq; WP_035012997.1; NZ_ARZY01000002.1.
DR AlphaFoldDB; W7QJB9; -.
DR STRING; 1328313.DS2_02318; -.
DR PATRIC; fig|1328313.3.peg.483; -.
DR eggNOG; COG0243; Bacteria.
DR OrthoDB; 9810782at2; -.
DR Proteomes; UP000019276; Unassembled WGS sequence.
DR GO; GO:1990204; C:oxidoreductase complex; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0045333; P:cellular respiration; IEA:UniProt.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019276}.
FT DOMAIN 6..62
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 885 AA; 97587 MW; 3EBB76A84C7B2966 CRC64;
MNKTAVKLKQ TTCPYCGVGC GIDVKVDGQA LTQVTGSSEH PANYGRLCVK GSSVLETNDV
SGRLLQPMIG DSQVSWDEAI NHVASGFNKV IEEFGPQAVA FYVSGQLLTE DYYVANKLMK
GYIGSANIDT NSRLCMSSAV AGYKRAFGSD TVPCNYEDLE DTDLLVLTGS NAAWTHPVLF
QRMERAKLLN PDMKVVVIDP RQSATTELAD LHIAIKPGSD VALFNGLLNY LHQHDCIDQN
YVNSFTEGFE TALANSQQWT IERVAEYCDL PLEQVTTYYQ WFAKSPTAIT FYCMGVNQSS
QGTDKCNAII NCHLATGKVG KKGSGPFSIT GQPNAMGGRE VGGLANMLAA HMDIGNPQHR
EYVQTFWRSP RIPEQVGSKA VDMFAKVKSG EIKAIWIMAT NPVVSLPNGN EVAQALKDCP
LVVVSDCNEN TDTSEWANVR LPATGWSEKN GTVTNSERRI SRQRGIMPPS GQAKHDWQII
CDVAKAMGFA SGFKFGHPAE IFDEHARLSG YENNGSRDFD ITGLAGLSEA EYDKLRPIQW
PVNRENPNGC ARMFENGRFY TKSGKAQFIT TEAKAPVQQT CKDYPFVCNS GRVRDQWHTM
TRTGKAAKLT AHVSEAFVAI HPADAEKLNL VDGQIAQLTS KFGRALLRVQ LDAGQRKGDV
FVPMHWNKQF ASQANINRLF APVVDPISGQ PELKHAAVAI EAYQADFYAV AYSRHAMQAN
TEYWSKAPNQ AGEQLLFAGQ GEVNDWLDWC QKHTAAEGEW LRVENNNDKS FKVVCYTQGQ
LEFVCYIQAT PFTEDMSWLS EIFMLQVFDR EELKALVSGI PTPEVAKGRQ ICSCFKVGEK
QIIEAIVDYG DDTVEKLGDR LQCGTNCGSC KTDLSGLIKS HCKSC
//
