ID W7QRN3_9ALTE Unreviewed; 383 AA.
AC W7QRN3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:EWH11657.1};
GN ORFNames=DS2_02490 {ECO:0000313|EMBL:EWH11657.1};
OS Catenovulum agarivorans DS-2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Catenovulum.
OX NCBI_TaxID=1328313 {ECO:0000313|EMBL:EWH11657.1, ECO:0000313|Proteomes:UP000019276};
RN [1] {ECO:0000313|EMBL:EWH11657.1, ECO:0000313|Proteomes:UP000019276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS-2 {ECO:0000313|EMBL:EWH11657.1,
RC ECO:0000313|Proteomes:UP000019276};
RX PubMed=24604650;
RA Shan D., Li X., Gu Z., Wei G., Gao Z., Shao Z.;
RT "Draft Genome Sequence of the Agar-Degrading Bacterium Catenovulum sp.
RT Strain DS-2, Isolated from Intestines of Haliotis diversicolor.";
RL Genome Announc. 2:e00144-14(2014).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWH11657.1}.
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DR EMBL; ARZY01000003; EWH11657.1; -; Genomic_DNA.
DR RefSeq; WP_035013064.1; NZ_ARZY01000003.1.
DR AlphaFoldDB; W7QRN3; -.
DR STRING; 1328313.DS2_02490; -.
DR PATRIC; fig|1328313.3.peg.519; -.
DR eggNOG; COG0626; Bacteria.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000019276; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR011821; O_succ_thio_ly.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR02080; O_succ_thio_ly; 1.
DR PANTHER; PTHR11808:SF75; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000019276}.
FT MOD_RES 198
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 383 AA; 41618 MW; 19F092EA09898DC9 CRC64;
MSKKNLATIA VRGGIESDGQ YNAVVPPIYL SSTYAFEGFD QKGPYDYSRC GNPSRDILAN
TLAELEHGAH GVVTATGTAA IHLVCQLLRP DDLLVVPHDC YGGSYRLFVN LAQRGAFKLQ
VINQTNQQEL DAAFAAKPKV IWVETPSNPL LRITDLADIC NRAKQTETLV AVDNTFLSPV
FQQPLTLGAD IVVHSTTKYI NGHSDVVGGV VVTKTKELGE ELAWWANCIG ITGSAFDSYM
TLRGVRTLVP RMKQHQENSL ALVDVLKDHP AVDKVYHPSL PSHPGHEIAK KQQHGFGAML
SFELKGTTDE VTRFIDKLEH FSLAESLGGT ESLVCHPSTM THAAMDEAAQ LKAGITQTLV
RFSVGIEDSS ELVADVKQAL DAL
//
