ID   W7SBQ0_LYSSH            Unreviewed;       715 AA.
AC   W7SBQ0;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=5-oxoprolinase {ECO:0000313|EMBL:EWH33843.1};
GN   ORFNames=P799_06545 {ECO:0000313|EMBL:EWH33843.1};
OS   Lysinibacillus sphaericus CBAM5.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX   NCBI_TaxID=1400869 {ECO:0000313|EMBL:EWH33843.1, ECO:0000313|Proteomes:UP000023555};
RN   [1] {ECO:0000313|EMBL:EWH33843.1, ECO:0000313|Proteomes:UP000023555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBAM5 {ECO:0000313|EMBL:EWH33843.1};
RX   PubMed=25685257; DOI=10.1186/1944-3277-10-2;
RA   Pena-Montenegro T.D., Lozano L., Dussan J.;
RT   "Genome sequence and description of the mosquitocidal and heavy metal
RT   tolerant strain Lysinibacillus sphaericus CBAM5.";
RL   Stand. Genomic Sci. 10:2-2(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWH33843.1}.
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DR   EMBL; AYKQ01000008; EWH33843.1; -; Genomic_DNA.
DR   AlphaFoldDB; W7SBQ0; -.
DR   HOGENOM; CLU_002157_1_2_9; -.
DR   Proteomes; UP000023555; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          39..206
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          233..523
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          554..705
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
SQ   SEQUENCE   715 AA;  79429 MW;  AAF3ED88B0E8906C CRC64;
     MNFYLKNTLN FLFILNIIYL ILIRNTVPII GTRRDGVLKI ATDIGGTFTD LVYTDEKGNL
     HFDKGHTTPG HFEDGILNVL GRHVTEDSLI ESFIHGSTVI INTLTERKGG VVGLITTKGF
     RDVLEIARGN RPDLYNFKYT KPAPFVERYL RQEIDERIDF KGNIMKALNR DEVGKIVRQF
     KELGVEAIAI SLIHGYKNPI HEQQLKVEIL NIWPEVYITL SSETIKEYRE YERTNTTVLN
     SYVKPIAHAY LKSLKEKLST IGITDHLKIM QSNGGTTSFD KAMELPINLV ESGPVAGMFG
     AAKLGELLNE SNIIAFDVGG TTAKCSLITD GKVNVTTDYY IERNEKFAGY PIKTPVVDIV
     EIGNGGGSIA RVDQFGSLKV GPDSAGANPG PVAYGLGNTQ PTITDANVYL GRLSLANFDN
     PVSIDKVEEA LIEAIAKPFH VSAEEAAQGI LDIANSNMLN ALKLISIRKG YDPEDFTMVA
     FGGGGPLHAI NLAEELGMKK VIIPYGSSVF SALGMMMTEY RQDYIQTSLM DFDHVHLADI
     QANINQAIES AYADAPLSKE HYYFEINYDL RYKGQEHAVK LNASNITIDD KGLLQLAEAF
     HVKHKQEFSF DLPTTPIELV NLHLTIYGKD EAVQFKELDF SHIDVSTCIK TKRNLYVKEK
     GWVEVNVYDQ QKLAPGYVIT GPAIVENPTS TVVINEKQSI EIDKYGNLIV EMEGK
//