ID W7TEE1_9STRA Unreviewed; 1592 AA.
AC W7TEE1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Dynein heavy chain {ECO:0000313|EMBL:EWM24537.1};
GN Name=DYHC8 {ECO:0000313|EMBL:EWM24537.1};
GN ORFNames=Naga_100175g4 {ECO:0000313|EMBL:EWM24537.1};
OS Nannochloropsis gaditana.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=72520 {ECO:0000313|EMBL:EWM24537.1, ECO:0000313|Proteomes:UP000019335};
RN [1] {ECO:0000313|EMBL:EWM24537.1, ECO:0000313|Proteomes:UP000019335}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-31 {ECO:0000313|EMBL:EWM24537.1,
RC ECO:0000313|Proteomes:UP000019335};
RX PubMed=23966634; DOI=10.1093/mp/sst120;
RA Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M.,
RA Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G.;
RT "Chromosome Scale Genome Assembly and Transcriptome Profiling of
RT Nannochloropsis gaditana in Nitrogen Depletion.";
RL Mol. Plant 7:323-335(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWM24537.1}.
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DR EMBL; AZIL01001189; EWM24537.1; -; Genomic_DNA.
DR EnsemblProtists; EWM24537; EWM24537; Naga_100175g4.
DR OrthoDB; 312195at2759; -.
DR Proteomes; UP000019335; Chromosome 13.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF314; CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000019335}.
FT DOMAIN 2..329
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 359..579
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 901..1010
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 1043..1205
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 1367..1588
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 45..79
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 207..234
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 563..590
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1592 AA; 177932 MW; A8F80B566B12372F CRC64;
MGLEKFAATQ KDVKDRQAAL ARKKIELSRK DAMANQKLRQ MVEDQNEAER KKASADQVAQ
ELSRQNETIA GRRKEVENEL AEAEPALLGA QKAVNSIKKA HLDEVRVLAR PPNPVRLTLE
AVLILLGEEK RDWNDVRKVI RRDDFIATVV NFDPEGITPK QVKDLQDLYL GLEEFEYDAV
QRASTACGPL NKWVVSLLNY SAILRRVQPL REEVAALQME SEKLQDRQTK IEGEITLLEN
SIALYKAEYA QAIRDIEGIK GEMDVVANKV KRAEALLASF ASEKERWHAS SASFQRQLSS
LAGDALLSAA FLTYAGIFDY KYRQRLLAEW ASILSALRLS YRPDLSLTDY LAHPTQQLAW
ASHGLPNDQL CLENAIILER AQHRYPLVID PSGQATKFLL QKFASRKVQT TSFADGAFLK
VLASAVRFGT PLLIQDVEER IDPLLNPVLN KEFQRTGGRT LLRLGNEDID FSPQFFVVLI
TRNSSARFPP DLCSRVSLVN FTDTPASLCS QALSRILRAE RPDVDKRRTE ILRLQGEQNV
RLRELEEGLL TEISAAECNI LVDDRVLKAL EELKAEAADL EKDVASTTAV MDELKYVSDV
YEPFALAVTQ VFFVMERLAS VHFLYQYPTQ YLLSILDNVL ARSPPDELVR KKGKDQGTQE
RIKDLELSFF AEVCRRVSKG LLQEDQLAFA LRLTLIHLQG AGQDREGRAN VHGKEERLDS
LMPTEEELEC LYKGPFSAAS SGLVNFTRRE ALEGAEEDEY LIPGIRIDIT QAKELRALSL
LPSFAFLLPA VSRDGPSWVA FMTSPRPENE VPDFDVALPV STTSTDGHAK DMLASMPGVQ
NTSTLPATRR AFLHLLLLKA LRPDRLMFVM ETYVSSVLGE DFPWRGLFDL AEVVREQSTA
ARPILLSAEA GFDASRTVDS LAEAEGGKGL RSVAMGSVEG YALADRYIAA GAQRGTWVLL
RNIHLCPHWL EKLERRLHNL SQPHPSFRLF LTSEIHPGLP SSLLRLSDVM VLEAPTGVKS
HVLRLLYEIP APRLDSGCVE KARLFFLVAW LHAILQERLR YLPWGWSRKY EFTQADALAA
LDVVEDWIER EGGRDRKQPS KDWHISPEDI PWAAIQSLLG QSVYGGKVEN IVDQAVLESF
ISDFFRPACF DMDFPLVSDL TVSLPEGDAA RRGGWEGREG RRADYMAWLE DLPSQNSTTW
LGLAASVEAD LSTAVGARIA RKVGDLWEDV VRDVVDPEEC LEEKKGVAEA RMGQKASLSK
ALLQRSQEWL ARIQSLVPGI KPGVLTPTPT PSPYPLAAIS SAAPSSDDSH TDDPLRQCLR
RNMEVGKEMI LRVQEDLNAT CRYLEQTLGD CHNQERTQDP DARKSRAKVE ATVTALSLDE
IPGPWRALHP RGAVDRGVGA WITDSIQRVE HGLALLSKLE KERNRKENIS SALGGVWLGA
LYNPEAFVTA TRQVVATQMC CSLEELDLAV EIKTPDSNTE QRGRDNAFAV VNLTLEGADL
EEGQLSLSSG AIRSQLPLAW LLWHKVGPQE RETRRLDGKA DKDDAPLVLP LYLDESRATL
IARMTVAQRE KDLRQTAAQW AQRGVALVAS RR
//
