ID W7W9B4_9BURK Unreviewed; 461 AA.
AC W7W9B4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=gluconokinase {ECO:0000256|ARBA:ARBA00012054};
DE EC=2.7.1.12 {ECO:0000256|ARBA:ARBA00012054};
GN ORFNames=Y694_04163 {ECO:0000313|EMBL:EWS57908.1};
OS Methylibium sp. T29-B.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=1437443 {ECO:0000313|EMBL:EWS57908.1, ECO:0000313|Proteomes:UP000019360};
RN [1] {ECO:0000313|EMBL:EWS57908.1, ECO:0000313|Proteomes:UP000019360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T29-B {ECO:0000313|EMBL:EWS57908.1,
RC ECO:0000313|Proteomes:UP000019360};
RA Gyula P., Szabo Z., Robotka H., Bihari Z.;
RT "Genome sequencing of the loss-of-function mutant Methylibium sp. T29-B.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+);
CC Xref=Rhea:RHEA:19433, ChEBI:CHEBI:15378, ChEBI:CHEBI:18391,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58759, ChEBI:CHEBI:456216;
CC EC=2.7.1.12; Evidence={ECO:0000256|ARBA:ARBA00001329};
CC -!- PATHWAY: Carbohydrate acid metabolism. {ECO:0000256|ARBA:ARBA00004761}.
CC -!- SIMILARITY: Belongs to the gluconokinase GntK/GntV family.
CC {ECO:0000256|ARBA:ARBA00008420}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWS57908.1}.
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DR EMBL; AZSN01000192; EWS57908.1; -; Genomic_DNA.
DR AlphaFoldDB; W7W9B4; -.
DR PATRIC; fig|1437443.4.peg.4190; -.
DR Proteomes; UP000019360; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046316; F:gluconokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02021; GntK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006001; Therm_gnt_kin.
DR PANTHER; PTHR43883:SF1; GLUCONOKINASE; 1.
DR PANTHER; PTHR43883; SLR0207 PROTEIN; 1.
DR Pfam; PF13671; AAA_33; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EWS57908.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 461 AA; 49998 MW; B75AF80611A05BDE CRC64;
MWKIKKPVTL PFVDFSTLEA RRRMCAEELQ LNRRLAPSIY QAIVPVTGEP DDPVLGGSGP
AIEWALVMRR FADGALFSER LAAGTLTPAL VDKLAERLAT FHAAAPRASA GTAYGSPARI
AADTCHLLEG LAAHGVQTQA FETWARSQAS ALDGHWRARQ REGWVREGHG DLHLANLFAE
GDEATAFDGI EFDPAMRWID VQADIAFTVM DLTAHGRTDL GFRFLDRWLA ATGDHAGLAV
LRYYLVYRAL VRAMVATLHP PVTEAPDYLG LARHWIAPAS GRLLLMHGVS GSGKSTIAEH
LLERAGAVRL RSDVERKRLH GLAALARSGA GLGDGPYDAA GTEQTYAYLR EAAHHALAAG
WPVIVDATFL SEAPRRMFRA LADQMRVPFS ILHCEAPRDV LAVRLAQRAA AASDASEGGT
EVLEHQLRTQ QLLAEDELAH VLPLAGDIDA LAAHWLAADA R
//
