GenomeNet

Database: UniProt
Entry: W7X2T7_TETTS
LinkDB: W7X2T7_TETTS
Original site: W7X2T7_TETTS 
ID   W7X2T7_TETTS            Unreviewed;      1075 AA.
AC   W7X2T7;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   05-JUL-2017, entry version 16.
DE   SubName: Full=Cation channel family protein {ECO:0000313|EMBL:EWS73610.1};
GN   ORFNames=TTHERM_000252417 {ECO:0000313|EMBL:EWS73610.1};
OS   Tetrahymena thermophila (strain SB210).
OC   Eukaryota; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=312017 {ECO:0000313|EMBL:EWS73610.1, ECO:0000313|Proteomes:UP000009168};
RN   [1] {ECO:0000313|Proteomes:UP000009168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX   PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA   Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA   Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA   Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA   Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M.,
RA   Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E.,
RA   Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K.,
RA   Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C.,
RA   Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M.,
RA   Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C.,
RA   Barbeau R.A., Hamilton E.P., Orias E.;
RT   "Macronuclear genome sequence of the ciliate Tetrahymena thermophila,
RT   a model eukaryote.";
RL   PLoS Biol. 4:1620-1642(2006).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GG662647; EWS73610.1; -; Genomic_DNA.
DR   RefSeq; XP_012653840.1; XM_012798386.1.
DR   STRING; 5911.EAR98847; -.
DR   GeneID; 24438038; -.
DR   KEGG; tet:TTHERM_000252417; -.
DR   Proteomes; UP000009168; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:GO_Central.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000009168};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    248    270       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    277    297       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    309    329       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    405    430       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    450    469       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    481    498       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      279    512       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1075 AA;  127339 MW;  FB7F761DA972E303 CRC64;
     MNDSNNSFIQ RSCFNEEKDD PFVKIVFVKG IDQLQGENSS TLRSITLNSS HNSSQSCQNN
     LDKISASVNS SRFIQTTQNE QNAEQTQLTK IYVNKEAKLD EDQQIELSQC DKQSLEEADD
     TEQEQQQKRQ SQALSQVSKH RRKHNIQLLG EESKKNWKKN WLNILYYVSK MKSIAKLTKR
     LFRHELLTAK QLKLIGDQTV NIEKLKKMEK YNFQKMMSFS NFNKILKYKT YKKIKINVKL
     YFSNIPSLLL SISNVYNKFI SYILSLIPIF NYLSNFYIFW QAIIFVCSFI NFIYLPFEFS
     FQNQRTIYLQ YYISIICPII FSLDIFIKAN TQTFQQGNQL RIHKQILKEY LTGTFFSDLV
     SIISLNQSLF ELRGFYFLFF LRFSRSLLIL DIFREKFFSK TYISGIISLI LLFASSLFFA
     HLFACFWYYV GTLSTQGWIN FYQLDKADIY SNYIYSYYFI IVTMTTIGYG DITAKTTEER
     LVMIFFTLIS CGIFGYIINS IGNILGDIKQ KSDKYLTELA KLNQYFKKYQ VSLQLQANVR
     RYLQFTYKEG IQDKLSALES LNNLSQHLQN QIKMDVVSRE LKQIGFLKQI CKEETFCQLS
     LQVQEKIYQP EQVILDQNEI KEPAIYIINY GRVLKNSQYD LSSKVNDIYE LKEKQSFGVI
     EFFMNLEASK FNYKSKELTS IYSLNLSAFL KVIKQDSEIY EKFCFLRDQI VYQKSLHLVK
     HFCESCRSLN HNLKECPCIF YKSRKLTIIK RYQQNIKETL RLTTRKKKLK ENSLMLNKQF
     VSQIILFQQD NINQLSLYDN SLSSIEDQHL FSSQKLHFSN TINSNQKNNR EDIEFKTSQL
     VDQLQLDQQE HEKIIIDIKS PLIVQRKKQE HEKLIGDEQI NTRSFQKLEA IEEQNEKQKL
     NQQPSILRNN YLSITSIQDN QCKNDQISVL QGIQTSIKDI FRFLIGENET IKWYKKHQVY
     QNMNSSAFKK MEAQLVSNKN IKSNFQIQDT NQNNRSSYVD QLMTHQNKQD IQNFCQDLDR
     MQKYKTYYPK FNYDIVIEKS NSRSYIQNIP LILRLIKLKR KTVNLKKRSK VIKQQ
//
DBGET integrated database retrieval system