ID W8AFA4_CERCA Unreviewed; 590 AA.
AC W8AFA4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Autophagy-related protein 16-1 {ECO:0000313|EMBL:JAB86920.1};
GN Name=A16L1 {ECO:0000313|EMBL:JAB86920.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB86920.1};
RN [1] {ECO:0000313|EMBL:JAB86920.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB86920.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GAMC01019635; JAB86920.1; -; mRNA.
DR EMBL; GAMC01019633; JAB86922.1; -; mRNA.
DR AlphaFoldDB; W8AFA4; -.
DR EnsemblMetazoa; XM_023303129.1; XP_023158897.1; LOC111591676.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF8; AUTOPHAGY-RELATED 16, ISOFORM F; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 12..200
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 300..333
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 344..385
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 386..427
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 444..469
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 220..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 69..96
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 227..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 65262 MW; AEF6B0ADB4D8824D CRC64;
MSADEPDWRQ SIVNRLRERS RNESRGKEII LQNNRLIDQA SQLTEDNLKL HVENEKLRTA
LSTGGGKDAT GAQLAIAALE KKLLAQQEEL TELHKRKGEN SQMIVDLSLI VEQQKKLIAE
KDKIIAEQKT ANISLRAEVD MLKSSLEQLK KLNATLLDEH TALKLSFSSL EEKLRGVQDE
NRCLLDRFMR YKSKDADKLN EENENFLRKR SDKLKRDLED AVREPNSTTH RNSGSPSQFG
DEGDTASLTS AGAGACNNGA VGGSPDYFQS LEEMLTPLPL PNFNPCIVSS SIPTNIFMKF
EAHDNETHAV KWSPVERLVA TGGGDRKVKL WDVGKGALEP RAVLGGSSAG INSVDFDSTG
SYILGTSNDY GARVWTVSDN RLRHTLTGHS GKVMAAKYLQ EPIKVVTGSH DRTLKVWDLR
SIACIETKFA GSSCNDLVTT DSLGSTIISG HYDKKLRFWD IRTEKQADDI LMPAKITSID
MTKDGYYLIC SIRDDTIKLI DLRKNQIISS FSHENFKLSC DWARASFNTC GSKLACGSAD
GLVYIWSILG DLEATLKGHN SAVNAVSWCP NSNALATVGK GKRCIIYTES
//
