ID W8ANX7_CERCA Unreviewed; 1203 AA.
AC W8ANX7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Retrovirus-related Pol polyprotein from transposon TNT 1-94 {ECO:0000313|EMBL:JAB86203.1};
DE Flags: Fragment;
GN Name=POLX {ECO:0000313|EMBL:JAB86203.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB86203.1};
RN [1] {ECO:0000313|EMBL:JAB86203.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB86203.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
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DR EMBL; GAMC01020352; JAB86203.1; -; mRNA.
DR AlphaFoldDB; W8ANX7; -.
DR GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProt.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR025724; GAG-pre-integrase_dom.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR013103; RVT_2.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR42648:SF22; RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON TNT 1-94; 1.
DR PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR Pfam; PF13976; gag_pre-integrs; 1.
DR Pfam; PF14223; Retrotran_gag_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF07727; RVT_2; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 232..246
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 449..625
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 710..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1203
FT /evidence="ECO:0000313|EMBL:JAB86203.1"
SQ SEQUENCE 1203 AA; 136347 MW; 2B23354A3FBD0DC8 CRC64;
MSFGGLYSIE KLDDFNYASW AIQMRSVLVH SELWPIVCGK CIKNEEATAA ESAAFDMQDE
KALASIMLSI KPSQLNHVKH SKTSLEAWNS LREVYQPSGP ARKITLFKKL LYLRKSEGNN
MKEHISEFYA VLEQLNEIGV IVPEEMLTII LLSSLNKSFE NFVVAIETRD TLPSLSALKI
KLLEEGERRL ENSKDKEIED SEQALVARAG VTKNDSYANK NKSSDKKYAN IKCFKCGKRG
HIASKCNDVK KLCSNNASLS VLASATLNNL NRECWIIDSG ATSHLCCERD LFSKYKECEE
KIMLADAHCI EAIGVGEVNL KCGNLMVKLQ NVLHVPSLKN NFLSVSKFLH YGLKVYFEKM
QVIIKTEKGE VLMRAKRQDG LYVFRYSTEK CCGTSVINNN EVHWHNRFGH LNFESLAEMA
NKNIVYGLKF KSQQQQNKCV TCARSKICVK KFPKVSENRA EKMCEVIHTD VCGPINIKSL
GGSRYFVTFI DDMSRYICVY FMKSRDEVFS KFKMFKEIVE KQNNCKIKVL RSDNGREYLS
REFGNYLKEN GIVRQLTVPH TPQQNGVAER ANRTLVEMAR SMLIHSESGE CFWAEAVSTA
AYLRNRAITK ALTSSTPFEK WTGKKPCVSH FKVFGSLAIA LDKTHKRKFQ PKGKKLIMVG
YSETSKAYRL YDPVAKTVIV SRDVIFVEDK YPGTFGTNNI SDLVTFEAEN QAEERTETEK
VDNEDPEANE ESNEQSDRVG RGRPKFVRTG KRGRPRKKRN MVNLLKAADV EIPNTVIEAM
NSKYSHQWED SMQKEYSALI KNDTWSLVDL PPGQKAIGCK WVFNVKQTAD GGVERFKSRL
VAKGCSQQYG VNFSETYSPV VRYATIRMLL ALAAEYKLFL HQMDVSTAYL NSDLHDIVYM
KQPEHFIDKQ FPKRVLQLKK ALYGLKQSGR EWNSKLESVL IKMNFKSCPS EPCVYTRNEK
GKYNIIAVYV DDLIIASSNM KDLSDIKAKI ADAFDVVDGG SLKYFLGMEI EREGDVGSIN
ICQSQYILNM LSQYGMENCK SVATPLEAGF QTYCDKEDCE RVNVTQYQSL IGALMYLAIS
TRPDILHSVS KLAQRNSDPH VEHKIGAKRI MRYLKGTVDY KLHYQKTGKP IQGYVDADWG
GDTNDRKSYT GCAFVAAGSV FSWESKKQNL VSLSSTEAEY VALSTAAKEA VYIKKLINET
GFN
//
