ID W8APB3_CERCA Unreviewed; 1527 AA.
AC W8APB3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Voltage-dependent T-type calcium channel subunit alpha-1H {ECO:0000313|EMBL:JAB87862.1};
DE Flags: Fragment;
GN Name=CAC1H {ECO:0000313|EMBL:JAB87862.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB87862.1};
RN [1] {ECO:0000313|EMBL:JAB87862.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB87862.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
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DR EMBL; GAMC01018693; JAB87862.1; -; mRNA.
DR EMBL; GAMC01018692; JAB87863.1; -; mRNA.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF230; CA[2+]-CHANNEL PROTEIN ALPHA[[1]] SUBUNIT T, ISOFORM F; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 497..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 775..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 841..859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 905..928
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 993..1019
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 457..728
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 773..1028
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 131..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1348..1402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1495..1527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1348..1371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1380..1394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1495..1516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB87862.1"
SQ SEQUENCE 1527 AA; 166013 MW; 046357D742411583 CRC64;
QQQQQQQGSN TNLSSCNLVT NSSSLLPSAL SSNSSMHSVV IDDISKSADT SPSGPIFVPT
TISTLSTPGM PLTPGTGSNG AVGGSGSGIG VGGGCSGGGG NAVSSIELSP LNAAVVVTTG
ATISTATTAT AAASSSLDTP PPPLTLPSAS ASAISTISPS SLSGMQRIPS LKRFRRSSSK
RKTKAATDAG SGAEDDEQQQ LNNGSDNSCL LAPQSNGSSS LRSDAFLSPS APRTPSSGAT
LTANNQTNQH KTKDTNRLSP QNSIRRLSTT LSIGSIPPLG SRRASACIFN SQLYQNLNQP
PKLYAPTAAH RRMSSFELAF SKSSQLNLHN LEANRKSMSY TNSKLDLDKW HMNLPESDML
QQYMQEREKR KGSISQYTRQ QQLLQKQQKE REQEESQQVS LGQQSNMQSS EHMSKFQILI
ERLKPTNLTE QRETYSLYIF AEDNRFRELC SWFVNQKWFD NVVLLFIALN CITLAMERPN
IPPTSNERLF LATANNVFTA IFTVEMLIKV VSTGMFYGSD AYFTSGWNIM DGSLVTISII
DLLMSLFSQS SSKIFGILRV FRLLRSLRPL RVINRAPGLK LVVQTLLSSL RPIGNIVLIC
CTFFIIFGIL GVQLFKGTFF YCEGENLKGV NTKADCYARG YEWKNRKYNF DDLGNALMSL
FVLSSRDGWV NIMYTGLDAV GEDLQPRVNY NEWRLLYFIA FILLVGFFVL NMFVGVVVEN
FHRCREEQEK EEKIRRAAKR ALQMEKKRRR MHEPPYYINY SPTRMFIHNV VTSKYFDLAI
AAVIGLNVVT MAMEYYSMPD VLVYTLKVFN YFFTAVFILE ASMKVLALGW PLYLKDRWNQ
LDVGIVLLSV FGIILEDWST QKFPINPTII RVMRVLRIAR VLKLLKMAKG MRALLDTVMQ
ALPQVGNLGL LFFLLFFIFA ALGVELFGRL ECSERNPCQG LGEHAHFANF GMAFLTLFRV
ATGDNWSGIM KDTLREDCDD ADDCVRDCCV SRVIAPIFFV IFVLMAQFVL VNVVVAVLMK
HLEESHKQME DEMDMEVELE RELVRGQEFE SEQKLCQQLE QQTQPPPPAR QLNKIKSLPK
NFTYSTPSLD KKFPSVLSGI GAGVGIGVGV SATGIGGRRQ TVQYFNQPNS IGLAELGRGT
QIGTAQGVGI GVGAAVGSSG VSGGGGSVGA TQALNARLNT TAAENGFDTK LQLQPTAGAL
GRRGRRSSTA FRSKRGLLAK ERSLDEQAIR RGTLESKRMS CDSLPWGGDS IDFRRGTIFE
SLESDGAGSP SSTYDVRSIR SEDVAATANA TARSSGASDA LSIVSASVIS EKITTPITAP
LATTAATAAL PLSGALTSAT APRRVYGRSL STDQAAQTSG GLSSGRGNSG GLLSVPRSMP
PRSRSGSTKQ LFKQQALDED PDMDENTLLL PIVAENSCDG NATTTSSGII ATDSGNSNGH
GNNGKLINNN TSNGANNRTT TANVNGAAAA AAVSAGEQIA LSKSDSADIM RIISERRRMD
QRDNSGNEDS DYKELLLVKS PHSSTDG
//
