ID W8AYV9_CERCA Unreviewed; 623 AA.
AC W8AYV9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|EMBL:JAB86101.1};
GN Name=PIAS3 {ECO:0000313|EMBL:JAB86101.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB86101.1};
RN [1] {ECO:0000313|EMBL:JAB86101.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB86101.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the PIAS family.
CC {ECO:0000256|ARBA:ARBA00005383}.
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DR EMBL; GAMC01020454; JAB86101.1; -; mRNA.
DR RefSeq; XP_004520545.1; XM_004520488.2.
DR AlphaFoldDB; W8AYV9; -.
DR EnsemblMetazoa; XM_004520488.3; XP_004520545.1; LOC101456739.
DR GeneID; 101456739; -.
DR OrthoDB; 20246at2759; -.
DR UniPathway; UPA00886; -.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd16790; SP-RING_PIAS; 1.
DR Gene3D; 2.60.120.780; PINIT domain; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR023321; PINIT.
DR InterPro; IPR038654; PINIT_sf.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF97; SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14324; PINIT; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51466; PINIT; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 2: Evidence at transcript level;
KW Ligase {ECO:0000313|EMBL:JAB86101.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 76..110
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 195..360
FT /note="PINIT"
FT /evidence="ECO:0000259|PROSITE:PS51466"
FT DOMAIN 392..473
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 68189 MW; 173872DBEF7CD20E CRC64;
MRKTRSQTQA EAAMANAGRT VSSTSNTPSV VSSSDNSNQP TMVGRGSANI QVAAVSAQKR
IPQPDHFKIK ECEEMVNLLR VVELQQILSF LNISFAGRKV DLQRRIINLL HSNYDLLAPK
IREVYTQSIA EQQAQQYGPT DPKRMYSHMQ MPPVPPNSAP GIPNAGQPTA VGGPPIAGVP
PTGPGVANNM VPFMNPIPTH IPIHPDVRLK KLAFYDVLGV LIKPSSLVPR NTQRIQEVPF
YFTLTPQQAT EIASNRDIRN SNKIEHAIQV QLRFCLLETS CEQEDCFPPS VSVKVNNKLC
QLPNVIPTNR PNVEPKRPPR PVNVTANVKL SPTVTNTITV QWCPDYTRGY CIAVYLVKKL
TSAQLLHRMK TKGVKPADYT RGLIKEKLTE DADCEIATTM LKVSLNCPLG KMKMSIPCRA
STCSHLQCFD ASLYLQMNER KPTWNCPVCD KAAIYDNLVI DGYFQEVLAS SLLKPDDTEI
QLHKDGSWST HSLRNEAQVI DTPTKPIEKV EVISDDIVIT TEDVKMVKAG APPATSNDQP
TSTTNSETVD LTLSDSDDDM PLAKRRPAIK QSAAANTASA VSTSNINING NGGNGNSAGN
GGSNANQRNA FAQQRTGVRV VLR
//
