ID W8B1N4_CERCA Unreviewed; 1469 AA.
AC W8B1N4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Titin {ECO:0000313|EMBL:JAB87161.1};
GN Name=TITIN {ECO:0000313|EMBL:JAB87161.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB87161.1};
RN [1] {ECO:0000313|EMBL:JAB87161.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB87161.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC protein kinase family. {ECO:0000256|ARBA:ARBA00006692}.
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DR EMBL; GAMC01019394; JAB87161.1; -; mRNA.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 3.
DR CDD; cd00096; Ig; 2.
DR CDD; cd11856; SH3_p47phox_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 14.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR47633:SF7; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47633; IMMUNOGLOBULIN; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 11.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 11.
DR SMART; SM00408; IGc2; 11.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 11.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 11.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..57
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 88..177
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 212..302
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 315..399
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 410..504
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 522..589
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 595..679
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 685..768
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 772..858
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 866..953
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 962..1056
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1061..1146
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1151..1242
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1249..1344
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1349..1445
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 1469 AA; 165734 MW; 8986571FECFC2A66 CRC64;
MYSICNYVAD NDEAINLVEG EKVYVIGRHS SEWWYVKKNI TEEEGWVPAQ YLMEPVEYTH
YVQKKLHEKI DKLPVFERPG PEEKPMAPRF IEKLQPIHTP DGYTVQFECK VEGMPRPQIA
WFRETAIIKP SQDFQMYYDD DNVATLIIRE VFPEDAGKFT CVAKNVAGFT SSTTELIVET
PLSDHGSDAT GLSRKSMSRE SSLADILEGI PPTFSRKPKA QYVDENTNVL LECRLVAVPE
PDIVWTFNGE EIDVKEIKNV RVVTESDMHM YCSVVHITKV KKSQEGTYEV IATNREGESR
LPIVLKVRTD EKEAPQILEP LRNTVVREGE SVVLTTQIVG NPRPKVTWYK DGKPITKNTK
SDKDTHTLTL ISPKAAESGE YTVKAENPLG SVETTANLTI EEPSSGNAEP PLFVERFEEQ
SVPQKGTIRL PAKVTGNPVP EVQWLFNNNP LYPSQRILQK YDGESIELII NDANPDTDSG
DYKCIASNPL GKTSHGARVI VEVDEVTFTK KLKKTISIEE IQSLTLECET SHVVTTKWFF
NGKELSGMDH RVVVEDGKVH KLVIRNTNLR DSGTYVCKVK NKETESTVEV LPRKPEFIKI
LEDYEVTEKN TAILDVEVST DNAEVVWYKD GEKITPENKN VEFVTEGKVR KLVIRDTTIH
DEGEYTCKLD EQECSAELTV IELPPEIVKP LKDVTVTQGE NAVFEVELSK GDALVKWLKD
GKELPLNEHV QLTIDGKKQT LRILDAKPTD IGKYSIQVGP QTSQAQLTVE EPLVNFVLPL
PDVTIATKGT DAEFTVELSQ PDVEVTWFKK AKPIKPNKKH EVFVEGTVRR FVIHDAEDDD
AGDISCTAAN ATTTSKLCVE EIQTLPIITS DKDQTIKVKE NDDVTMTVKF TGTPKPEAEW
STTKNVIVKN KHLIPTLDEQ SATLTIKKVV DDDEGLYTVR LKNPVGDVEA TLNLIIMRKP
TAPGAPEPLE VTHDSITLFW KAPEDDGKCE ITEYVLEYQD VKEERWIEIR KIKDTTYTIS
KLKIETEYVF RAIAINDVGP SPPSPLSPPI RLVAEVKKEK PTVQEPLQDI VTELNKEITL
SCVFGGIPEP KVTWKKNGEV IKTKTMRYEN RVSKYTIEKT TIETEATYTC VAENDMGSVE
TSCRIILQEK PTIDIDEKYL AQKIRAGTTL NIPATVRGYP QPKATWYRET TEQTTTTERV
TIETTETTTT YSLEKVTRED SGRYKITATN TSGTATTECT IQVIDKPSRP RSIEIKEMKK
DAITLAWTPP IDDGGLELNK YVLEKCDLQN NLWMKVADLE KDIHSYAVQK LSMNSQYMFR
VVAANPVGES EPVESDPVTI TRKFEKPSAP RGPTEVFGMT DTAFTLAWEP SESDGGSRII
EYIVEIKEFH ETEYRLLGST TGNVTNILVS DVIKDRAYQF KIYAKNEVGI SEALETEDKI
VVSRKISKCL NILFYLLFLQ RIVYILLYK
//
